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Ring Finger Protein 34 产品

(Ring Finger Protein 34 (RNF34))

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The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012].

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Featured Ring Finger Protein 34 Categories

Ring Finger Protein 34 抗体

High quality antibodies with extensive validation data.

Ring Finger Protein 34 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Ring Finger Protein 34 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7151192
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN529210
Quantity 50 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN2476355
Quantity 0.1 mg
Datasheet Datasheet

Recommended Ring Finger Protein 34 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207372
Quantity 96 tests
Datasheet Datasheet

Recommended Ring Finger Protein 34 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275519
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275520
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124915
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Ring Finger Protein 34 Products

He, Zhu, Zhang, Geng, Gong, Geng, Zhang, Zhang, Liu, Peng, Wang, Wang, Liu, Wan, Gong, Wei, Zhong: "RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation." in: The EMBO journal, (2019) (PubMed).

Konishi, Sasaki, Watanabe, Kitayama, Nagawa: "Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kappaB and upregulation of BCL-2 and BCL-XL." in: Oncogene, Vol. 25, Issue 22, pp. 3160-9, (2006) (PubMed).

Konishi, Sasaki, Watanabe, Kitayama, Nagawa: "Overexpression of hRFI (human ring finger homologous to inhibitor of apoptosis protein type) inhibits death receptor-mediated apoptosis in colorectal cancer cells." in: Molecular cancer therapeutics, Vol. 4, Issue 5, pp. 743-50, (2005) (PubMed).

Sasaki, Watanabe, Konishi, Kitayama, Nagawa: "Effects of expression of hRFI on adenoma formation and tumor progression in colorectal adenoma-carcinoma sequence." in: Journal of experimental & clinical cancer research : CR, Vol. 23, Issue 3, pp. 507-12, (2004) (PubMed).

Sasaki, Nakamura, Arakawa, Mori, Watanabe, Nagawa, Croce: "Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer." in: Oncogene, Vol. 21, Issue 32, pp. 5024-30, (2002) (PubMed).

Synonyms and alternative names related to Ring Finger Protein 34

ring finger protein 34 (RNF34), E3 ubiquitin-protein ligase RNF34 (rnf34), ring finger protein 34 (Rnf34), ring finger protein 34a (rnf34a), ring finger protein 34b (rnf34b), Residual feed intake (RFI), AW061037, AW536122, BC004042, C88279, CARP-1, CARP1, fi35g06, hRFI, Momo, RFI, RIF, RIFF, rnf34, wu:fi35g06, zgc:114043, zgc:171755

Protein level used designations for Ring Finger Protein 34

  • E3 ubiquitin-protein ligase RNF34
  • FYVE-RING finger protein MOMO
  • RING finger protein RIFF
  • caspase regulator CARP1
  • caspases-8 and -10-associated RING finger protein 1
  • human RING finger homologous to inhibitor of apoptosis protein
  • phafin 1
  • phafin-1
  • RING finger protein MOMO
  • uncharacterized protein LOC568879
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