This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. [provided by RefSeq, Jul 2008].
Latest Publications for our Ring Finger Protein 1 抗体
Hu, Li, Zhang, Zheng: "HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5582-93, (2014) (PubMed).
Vidal: "Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression." in: The International journal of developmental biology, Vol. 53, Issue 2-3, pp. 355-70, (2009) (PubMed).
Aliases for Ring Finger Protein 1 抗体
ring finger protein 1 (RING1) 抗体 ring finger protein 1 (Ring1) 抗体 ring finger protein 1 S homeolog (ring1.S) 抗体 ring finger protein 1 L homeolog (ring1.L) 抗体 bap-1 抗体 bap1 抗体 ding 抗体 hipi3 抗体 ring1 抗体 RING1A 抗体 Ring1A 抗体 ring1a 抗体 ring1b 抗体 ring1b-B 抗体 ring2 抗体 RNF1 抗体 rnf1 抗体 rnf2-a 抗体 rnf2-b 抗体