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RIN2 产品

(Ras and Rab Interactor 2 (RIN2))

Categories

The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011].

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Featured RIN2 Categories

RIN2 抗体

High quality antibodies with extensive validation data.

RIN2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RIN2 抗体

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Reactivity
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Reactivity Human
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Cat. No. ABIN565735
Quantity 100 μg
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Cat. No. ABIN527065
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Reactivity Human
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Cat. No. ABIN565734
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Recommended RIN2 蛋白

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Quantity 10 μg
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3095019
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Reactivity Mouse
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Cat. No. ABIN3137102
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Latest Publications for our RIN2 Products

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Sandri, Caccavari, Valdembri, Camillo, Veltel, Santambrogio, Lanzetti, Bussolino, Ivaska, Serini: "The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling." in: Cell research, Vol. 22, Issue 10, pp. 1479-501, (2012) (PubMed).

Synonyms and alternative names related to RIN2

Ras and Rab interactor 2 (Rin2), Ras and Rab interactor 2 (RIN2), Ras and Rab interactor 2 (rin2), 2010003K16Rik, 4632403N06Rik, AW821980, MACS, rassf4, RASSF4, RIN2, RINL

Protein level used designations for RIN2

  • ras and Rab interactor 2
  • Ras and Rab interactor 2
  • RAB5 interacting protein 2
  • ras and Rab interactor 2-like
  • RAS association (RalGDS/AF-6) domain containing protein JC265
  • RAS association domain family 4
  • RAS inhibitor JC265
  • RAS interaction/interference protein 2
  • ras interaction/interference protein 2
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