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RHOC 产品

(Ras Homolog Gene Family, Member C (RHOC))

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This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

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Featured RHOC Categories

RHOC 抗体

High quality antibodies with extensive validation data.

RHOC ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RHOC 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RHOC 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (6)
Cat. No. ABIN513475
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN513476
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN2854791
Quantity 100 μL
Datasheet Datasheet

Recommended RHOC ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969837
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1155612
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1155615
Quantity 96 tests
Datasheet Datasheet

Recommended RHOC 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1318024
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124787
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318026
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our RHOC Products

He, Wei, Du, Meng, Zheng, Lai, Yao, Zhou, Wang, Luo, Ma, Zhang: "Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells." in: Cellular signalling, Vol. 31, pp. 87-95, (2017) (PubMed).

Yang, Liang, Zhou, Mi, Ma, Fan, Ning, Wang, Wei, Li: "Knockdown of RHOC by shRNA suppresses invasion and migration of cholangiocellular carcinoma cells via inhibition of MMP2, MMP3, MMP9 and epithelial-mesenchymal transition." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 5255-61, (2017) (PubMed).

Han, Yang, Li, Li, Zheng, Yu, Zhang, Zheng, Yi, Li, Guo, Zhou: "RhoB/ROCK mediates oxygen-glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia." in: Cell and tissue research, Vol. 366, Issue 2, pp. 411-425, (2016) (PubMed).

Saito, Ohmasa, Shomori, Dimitriadis, Ohiwa, Shimizu, Tsounapi, Kinoshita, Satoh: "Rhos and Rho kinases in the rat prostate: their possible functional roles and distributions." in: Molecular and cellular biochemistry, Vol. 358, Issue 1-2, pp. 207-13, (2011) (PubMed).

Han, Li, Hu, Yu, Zheng, Guo, Zheng, Yi, Zhou: "Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation." in: Endocrinology, Vol. 151, Issue 4, pp. 1732-42, (2010) (PubMed).

Quinn, Brindley, Weller, Kaludov, Kondratowicz, Hunt, Sinn, McCray, Stein, Davidson, Flick, Mandell, Staplin, Maury, Chiorini: "Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors." in: Journal of virology, Vol. 83, Issue 19, pp. 10176-86, (2009) (PubMed).

Sousa, Espreafico: "Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets." in: BMC cancer, Vol. 8, pp. 19, (2008) (PubMed).

Schwartz, Tessema, Buranda, Pylypenko, Rak, Simons, Surviladze, Sklar, Wandinger-Ness: "Flow cytometry for real-time measurement of guanine nucleotide binding and exchange by Ras-like GTPases." in: Analytical biochemistry, Vol. 381, Issue 2, pp. 258-66, (2008) (PubMed).

Synonyms and alternative names related to RHOC

ras homolog family member C L homeolog (rhoc.L), ras homolog family member C (RHOC), ras homolog family member C (rhoc), ras homolog family member C (Rhoc), AI324259, ARH9, Arh9, ARHC, Arhc, CRHOC, H9, LOC100221682, RHOH9

Protein level used designations for RHOC

  • ras homolog gene family, member C
  • rho-related GTP-binding protein RhoC
  • RAS-related homolog 9
  • oncogene RHO H9
  • rho cDNA clone 9
  • rhoC GTPase
  • small GTP binding protein RhoC
  • SIG-61
  • aplysia ras-related homolog 9 (RhoC)
  • ras homolog 9 (RhoC)
  • silica-induced gene 61 protein
  • GTP-binding protein
  • GTPase cRhoC
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