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RGS4 产品

(Regulator of G-Protein Signaling 4 (RGS4))
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured RGS4 Categories

RGS4 抗体

High quality antibodies with extensive validation data.

RGS4 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RGS4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RGS4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN2856953
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7259747
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7269898
Quantity 100 μL
Datasheet Datasheet

Recommended RGS4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Goat
Analytical Method Competition ELISA
Validations
Cat. No. ABIN995349
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN995350
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN995351
Quantity 96 tests
Datasheet Datasheet

Recommended RGS4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1317968
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7529178
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406002
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our RGS4 Products

Jung, Son, Lee, Roh, Kang, Cho, Choi, Kim: "Decreased levels of RGS4 in the paraventricular nucleus facilitate GABAergic inhibition during the acute stress response." in: Biochemical and biophysical research communications, Vol. 472, Issue 1, pp. 276-80, (2016) (PubMed).

Rivero, Gabilondo, García-Sevilla, La Harpe, Morentín, Javier Meana: "Characterization of regulators of G-protein signaling RGS4 and RGS10 proteins in the postmortem human brain." in: Neurochemistry international, Vol. 57, Issue 7, pp. 722-9, (2010) (PubMed).

Xie, Wolff, Wei, Wang, Deng, Kirui, Jiang, Qin, Abel, Tu: "Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4." in: Cancer research, Vol. 69, Issue 14, pp. 5743-51, (2009) (PubMed).

Iankova, Chavey, Clapé, Colomer, Guérineau, Grillet, Brunet, Annicotte, Fajas: "Regulator of G protein signaling-4 controls fatty acid and glucose homeostasis." in: Endocrinology, Vol. 149, Issue 11, pp. 5706-12, (2008) (PubMed).

Synonyms and alternative names related to RGS4

regulator of G protein signaling 4 (RGS4), regulator of G-protein signaling 4 (Rgs4), regulator of G protein signaling 4 (Rgs4), regulator of G-protein signaling 4 (RGS4), AA004315, AA597169, ESTM48, ESTM50, RGP4, SCZD9

Protein level used designations for RGS4

  • schizophrenia disorder 9
  • regulator of G-protein signalling 4
  • RGP4
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