Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Find RGS10 抗体 for a variety of species such as anti-Human RGS10, anti-Mouse RGS10, anti-Rat RGS10. The species listed below are among those available. Click on a link to go to the corresponding products.
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Burgon, Lee, Nixon, Peralta, Casey: "Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10)." in: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 32828-34, (2001) (PubMed).
Chatterjee, Fisher: "Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs." in: The Journal of biological chemistry, Vol. 275, Issue 31, pp. 24013-21, (2000) (PubMed).
Hunt, Fields, Casey, Peralta: "RGS10 is a selective activator of G alpha i GTPase activity." in: Nature, Vol. 383, Issue 6596, pp. 175-7, (1996) (PubMed).
Aliases for RGS10 抗体
regulator of G-protein signaling 10 (RGS10) 抗体 regulator of G-protein signaling 10 L homeolog (rgs10.L) 抗体 regulator of G protein signaling 10 (RGS10) 抗体 regulator of G-protein signaling 10 (rgs10) 抗体 regulator of G-protein signaling 10 (Rgs10) 抗体 regulator of G-protein signalling 10 (Rgs10) 抗体 2310010N19Rik 抗体 MGC82511 抗体 RGS10 抗体
