RFWD3 产品
(Ring Finger and WD Repeat Domain 3 (RFWD3))
Categories
E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
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Featured RFWD3 Categories
Recommended RFWD3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6257465
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7187949
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN565828
Quantity
100 μg
Datasheet
Datasheet
Recommended RFWD3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207368
Quantity
96 tests
Datasheet
Datasheet
Recommended RFWD3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317874
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094992
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136488
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to RFWD3
ring finger and WD repeat domain 3 (Rfwd3), ring finger and WD repeat domain 3 (RFWD3), BC027246, RFWD3, RGD1305243, RNF201Protein level used designations for RFWD3
- ring finger and WD repeat domain 3
- RING finger and WD repeat domain-containing protein 3-like
- E3 ubiquitin-protein ligase RFWD3
- RING finger and WD repeat domain-containing protein 3
- RING finger protein 201
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