Retinoblastoma 1 产品
(Retinoblastoma 1 (RB1))
Categories
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008].
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Featured Retinoblastoma 1 Categories
Retinoblastoma 1 抗体
High quality antibodies with extensive validation data.
Retinoblastoma 1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Retinoblastoma 1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Retinoblastoma 1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
- (1)
- (1)
Cat. No.
ABIN675294
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN712946
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (1)
- (3)
Cat. No.
ABIN6264703
Quantity
100 μL
Datasheet
Datasheet
Recommended Retinoblastoma 1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6574260
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN5526749
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969918
Quantity
96 tests
Datasheet
Datasheet
Recommended Retinoblastoma 1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317543
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505541
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7393433
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Retinoblastoma 1 Products
: "IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1445-1450, (2018) (PubMed).: "EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop." in: Nature communications, Vol. 8, Issue 1, pp. 877, (2018) (PubMed).
: "ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells." in: Nanoscale research letters, Vol. 12, Issue 1, pp. 322, (2017) (PubMed).
: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." in: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).
: "Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs." in: Cell cycle (Georgetown, Tex.), Vol. 16, Issue 2, pp. 172-178, (2017) (PubMed).
: "A Point Mutation in DNA Polymerase β (POLB) Gene Is Associated with Increased Progesterone Receptor (PR) Expression and Intraperitoneal Metastasis in Gastric Cancer." in: Journal of Cancer, Vol. 7, Issue 11, pp. 1472-80, (2016) (PubMed).
: "Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus." in: The international journal of biochemistry & cell biology, Vol. 65, pp. 104-12, (2016) (PubMed).
: "Quantitative Label-Free Phosphoproteomics Reveals Differentially Regulated Protein Phosphorylation Involved in West Nile Virus-Induced Host Inflammatory Response." in: Journal of proteome research, Vol. 14, Issue 12, pp. 5157-68, (2016) (PubMed).
: "Molecular Determinants for the Inactivation of the Retinoblastoma Tumor Suppressor by the Viral Cyclin-dependent Kinase UL97." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19666-80, (2015) (PubMed).
: "MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes." in: Cell communication and signaling : CCS, Vol. 12, pp. 66, (2015) (PubMed).
Synonyms and alternative names related to Retinoblastoma 1
RB transcriptional corepressor 1 (RB1), RB transcriptional corepressor like 1 (RBL1), RB transcriptional corepressor 1 (Rb1), RB transcriptional corepressor 1 (rb1), retinoblastoma 1 (rb1), OSRC, p105-Rb, P105-RB, pp110, PP110, pRb, RB, Rb, Rb-1, RB11, zgc:154147Protein level used designations for Retinoblastoma 1
- retinoblastoma suspectibility protein
- retinoblastoma-associated protein
- retinoblastoma-like protein 1
- pp105
- Retinoblastoma 1 (including osteosarcoma)
- pRb
- rb
- retinoblastoma 1 (including osteosarcoma)
- retinoblastoma protein
- retinoblastoma, susceptibility
- Retinoblastoma-associated protein
- retinoblastoma 1
- retinoblastoma-associated protein-like
- spc
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