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RDH8 产品

(Retinol Dehydrogenase 8 (RDH8))

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All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors\; hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin (Rando, 2001 [PubMed 11710234]). This is a rate-limiting step in the visual cycle (Saari et al., 1998 [PubMed 9667000]).[supplied by OMIM, Mar 2008].

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Featured RDH8 Categories

RDH8 抗体

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to RDH8

retinol dehydrogenase 8 (all-trans) (RDH8), retinol dehydrogenase 8 (Rdh8), retinol dehydrogenase 8a (rdh8a), retinol dehydrogenase 8 (all-trans) (Rdh8), retinol dehydrogenase 8 (MCYG_01756), retinol dehydrogenase 8 (MGYG_04308), retinol dehydrogenase 8 (rdh8), cb501, Gm182, PRRDH, prRDH, rdh8, SDR28C2, zf1.1, zfprRDH2, zgc:73081

Protein level used designations for RDH8

  • photoreceptor outer segment all-trans retinol dehydrogenase
  • retinol dehydrogenase 8
  • short chain dehydrogenase/reductase family 28C, member 2
  • zf 1.1
  • retinol dehydrogenase 8 (all-trans)
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