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RCC1 产品

(Regulator of Chromosome Condensation 1 (RCC1))

Categories

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly.

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Featured RCC1 Categories

RCC1 抗体

High quality antibodies with extensive validation data.

RCC1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RCC1 抗体

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Latest Publications for our RCC1 Products

Hayes, Duan, Bowen, Kalab, Rothstein: "C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import." in: eLife, Vol. 9, (2020) (PubMed).

Gillon, Nielsen, Steel, Cornwall, Sheard: "Exercise attenuates age-associated changes in motoneuron number, nucleocytoplasmic transport proteins and neuromuscular health." in: GeroScience, Vol. 40, Issue 2, pp. 177-192, (2018) (PubMed).

Wang, Xue, Hu, Wei, Zhang, Ge, Liang: "Structure-dependent mitochondrial dysfunction and hypoxia induced with single-walled carbon nanotubes." in: Small (Weinheim an der Bergstrasse, Germany), Vol. 10, Issue 14, pp. 2859-69, (2014) (PubMed).

Li, Zheng: "Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells." in: Genes & development, Vol. 18, Issue 5, pp. 512-27, (2004) (PubMed).

Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).

Cushman, Stenoien, Moore: "The dynamic association of RCC1 with chromatin is modulated by Ran-dependent nuclear transport." in: Molecular biology of the cell, Vol. 15, Issue 1, pp. 245-55, (2003) (PubMed).

Ciarallo, Subramaniam, Hung, Lee, Kotchetkov, Sandhu, Milic, Slingerland: "Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest." in: Molecular and cellular biology, Vol. 22, Issue 9, pp. 2993-3002, (2002) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Bilbao-Cortés, Hetzer, Längst, Becker, Mattaj: "Ran binds to chromatin by two distinct mechanisms." in: Current biology : CB, Vol. 12, Issue 13, pp. 1151-6, (2002) (PubMed).

Nemergut, Lindsay, Brownawell, Macara: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, (2002) (PubMed).

Synonyms and alternative names related to RCC1

regulator of chromosome condensation 1 (rcc1), regulator of chromosome condensation 1 (RCC1), regulator of chromosome condensation 1 L homeolog (rcc1.L), Regulator of chromosome condensation 1 (Rcc1), N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted (RCC1), regulator of chromosome condensation 1 S homeolog (rcc1.S), regulator of chromosome condensation 1 (Rcc1), 4931417M11Rik, AI326872, BJ1, CG10480, CG18640 (Bj1), Chc1, CHC1, chc1-a, chc1-b, Dmel\\CG10480, dRCC1, inxs, MGC115703, MGC132085, RanGEF, rcc1, RCC1, Rcc1, RCC1-I, sdt, SNHG3-RCC1, wu:fj77f08, xrcc1, zgc:65796, zgc:77114

Protein level used designations for RCC1

  • chromosome condensation 1
  • fj77f08
  • regulator of chromosome condensation
  • regulator of chromosome condensation 1
  • RCC1 protein
  • Bj1-PA
  • Bj1-PB
  • Bj1-PC
  • CG10480-PA
  • CG10480-PB
  • CG10480-PC
  • in excess
  • side-out
  • possible fragment of potential guanine nucleotide exchange factor
  • SNHG3-RCC1 readthrough transcript
  • cell cycle regulatory protein
  • guanine nucleotide-releasing protein
  • chromosome condensation protein 1
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