RBM4 产品
(RNA Binding Motif Protein 4 (RBM4))
Categories
RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of EIF2C2- containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro (By similarity).
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Featured RBM4 Categories
Recommended RBM4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6264671
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7168345
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7247819
Quantity
200 μL
Datasheet
Datasheet
Recommended RBM4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6212020
Quantity
96 tests
Datasheet
Datasheet
Recommended RBM4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317607
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094945
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136387
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to RBM4
RNA binding motif protein 4.1 (rbm4.1), RNA binding motif protein 4 (RBM4), RNA-binding protein 14 (LOC610648), RNA binding motif protein 4 (Rbm4), RNA-binding protein lark (LARK), 4921506I22Rik, LARK, lark, Lark1, Mlark, rbm4, Rbm4, RBM4A, Rbm4a, rna-bp4, wu:fc31f07, wu:fc57h11, ZCCHC21, ZCRB3A, zgc:56302Protein level used designations for RBM4
- RNA binding motif protein 4
- RNA-binding motif protein 4.1
- RNA-binding protein 4.1
- RNA-binding motif protein 4a
- RNA-binding protein 4
- lark homolog
- transcriptional coactivator CoAZ
- zinc finger CCHC-type and RNA binding motif 3A
- RNA-binding motif protein 4
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