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RBM25 产品

(RNA Binding Motif Protein 25 (RBM25))

Categories

RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA (By similarity).

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Featured RBM25 Categories

RBM25 抗体

High quality antibodies with extensive validation data.

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Recommended RBM25 ELISA试剂盒

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Latest Publications for our RBM25 Products

Becker, Barysch, Karaca, Dittner, Hsiao, Berriel Diaz, Herzig, Urlaub, Melchior: "Detecting endogenous SUMO targets in mammalian cells and tissues." in: Nature structural & molecular biology, Vol. 20, Issue 4, pp. 525-31, (2013) (PubMed).

Maubach, Lim, Zhuo: "Nuclear cathepsin F regulates activation markers in rat hepatic stellate cells." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4238-48, (2008) (PubMed).

Zhou, Ou, Cho, Benz, Huang: "Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection." in: Molecular and cellular biology, Vol. 28, Issue 19, pp. 5924-36, (2008) (PubMed).

Synonyms and alternative names related to RBM25

RNA binding motif protein 25b (rbm25b), RNA binding motif protein 25 (Rbm25), RNA binding motif protein 25 S homeolog (rbm25.S), RNA binding motif protein 25 (rbm25), RNA binding motif protein 25 (RBM25), putative rna binding motif protein 25 (Smp_078610), 2600011C06Rik, 2610015J01Rik, A130095G20Rik, AI159652, AL023075, AU043498, fi03e10, fSAP94, NET52, RED120, rnpc7, RNPC7, s164, S164, si:ch211-105d18.5, Snu71, wu:fi03e10, zgc:56208

Protein level used designations for RBM25

  • RNA-binding protein 25
  • RNA binding motif protein 25
  • RNA-binding protein 25-like
  • Arg/Glu/Asp-rich protein, 120 kDa
  • RNA-binding motif protein 25
  • RNA-binding region (RNP1, RRM) containing 7
  • RNA-binding region-containing protein 7
  • U1 small nuclear ribonucleoprotein 1SNRP homolog
  • arg/Glu/Asp-rich protein of 120 kDa
  • functional spliceosome-associated protein 94
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