Raptor 产品
(Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))
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This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
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Featured Raptor Categories
Raptor 抗体
High quality antibodies with extensive validation data.
Raptor ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Raptor 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Raptor 抗体
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Recommended Raptor ELISA试剂盒
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Latest Publications for our Raptor Products
: "Contractile activity-induced mitochondrial biogenesis and mTORC1." in: American journal of physiology. Cell physiology, Vol. 303, Issue 5, pp. C540-7, (2012) (PubMed).: "Raptor, a positive regulatory subunit of mTOR complex 1, is a novel phosphoprotein of the rDNA transcription machinery in nucleoli and chromosomal nucleolus organizer regions (NORs)." in: Cell cycle (Georgetown, Tex.), Vol. 10, Issue 18, pp. 3140-52, (2011) (PubMed).
: "Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study." in: The Lancet. Oncology, Vol. 12, Issue 4, pp. 361-8, (2011) (PubMed).
: "Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations." in: PLoS genetics, Vol. 6, Issue 10, pp. e1001178, (2010) (PubMed).
: "mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 26, pp. 11823-8, (2010) (PubMed).
: "A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1." in: Molecular and cellular biology, Vol. 30, Issue 2, pp. 481-95, (2009) (PubMed).
: "ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cells." in: American journal of physiology. Cell physiology, Vol. 293, Issue 1, pp. C55-63, (2007) (PubMed).
: "Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation." in: Circulation research, Vol. 101, Issue 6, pp. 560-9, (2007) (PubMed).
: "Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one." in: The Journal of biological chemistry, Vol. 282, Issue 33, pp. 24463-70, (2007) (PubMed).
: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).
Synonyms and alternative names related to Raptor
regulatory associated protein of MTOR complex 1 (RPTOR), regulatory associated protein of MTOR, complex 1 (Rptor), regulatory associated protein of MTOR, complex 1 L homeolog (rptor.L), regulatory associated protein of MTOR, complex 1 (rptor), 4932417H02Rik, KOG1, Mip1, mKIAA1303, Rap, Raptor, raptor, RGD1311784Protein level used designations for Raptor
- p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats
- raptor
- regulatory-associated protein of mTOR
- p150 target of rapamycin (TOR)-scaffold protein
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