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RAP1A 产品

(RAP1A, Member of RAS Oncogene Family (RAP1A))
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured RAP1A Categories

RAP1A 抗体

High quality antibodies with extensive validation data.

RAP1A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RAP1A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RAP1A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN3021200
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (2)
  • (4)
Cat. No. ABIN969561
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (1)
  • (3)
Cat. No. ABIN519632
Quantity 100 μg
Datasheet Datasheet

Recommended RAP1A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969828
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969827
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969829
Quantity 96 tests
Datasheet Datasheet

Recommended RAP1A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1317390
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124776
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2131496
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our RAP1A Products

Chinigò, Grolez, Audero, Bokhobza, Bernardini, Cicero, Toillon, Bailleul, Visentin, Ruffinatti, Brysbaert, Lensink, De Ruyck, Cantelmo, Fiorio Pla, Gkika: "TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells." in: Cancers, Vol. 14, Issue 9, (2022) (PubMed).

Stott, Barrese, Suresh, Masoodi, Greenwood: "Investigating the Role of G Protein βγ in Kv7-Dependent Relaxations of the Rat Vasculature." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 9, pp. 2091-2102, (2019) (PubMed).

Chen, Chuang, Huang, Fang, Huang, Tsai, Su, Shiu, Leu, Chien: "Overexpression of Rap-1A indicates a poor prognosis for oral cavity squamous cell carcinoma and promotes tumor cell invasion via Aurora-A modulation." in: The American journal of pathology, Vol. 182, Issue 2, pp. 516-28, (2013) (PubMed).

Severson, Lee, Capaldo, Nusrat, Parkos: "Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1916-25, (2009) (PubMed).

Dao, Dupuy, Gavet, Caron, de Gunzburg: "Dynamic changes in Rap1 activity are required for cell retraction and spreading during mitosis." in: Journal of cell science, Vol. 122, Issue Pt 16, pp. 2996-3004, (2009) (PubMed).

Branham, Bustos, De Blas, Rehmann, Zarelli, Treviño, Darszon, Mayorga, Tomes: "Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis." in: The Journal of biological chemistry, Vol. 284, Issue 37, pp. 24825-39, (2009) (PubMed).

Chu, Awasthi, White, Chrzanowska-Wodnicka, Malarkannan: "Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3373-83, (2008) (PubMed).

Synonyms and alternative names related to RAP1A

RAP1A, member of RAS oncogene family (RAP1A), RAS-related protein 1a (Rap1a), RAP1A, member of RAS oncogene family (Rap1a), RAP1A, member of RAS oncogene family a (rap1aa), RAP1A, member of RAS oncogene family L homeolog (rap1a.L), AI848598, G-22K, KREV-1, Krev-1, krev-1, KREV1, krev1, RAP-1A, RAP1, Rap1, rap1, rap 1A, SMGP21, wu:fc66g06, zgc:86676

Protein level used designations for RAP1A

  • C21KG
  • G-22K
  • GTP-binding protein smg p21A
  • RAS-related protein RAP1A
  • Ras-related protein Krev-1
  • ras-related protein Rap-1A
  • RAP1A, member of RAS oncogene family
  • GTP-binding protein SMG-P21A
  • ras-related protein Krev-1
  • RAS-related protein 1a
  • Rap1b
  • GTP-binding protein smg-p21A
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