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RANGAP1 产品

(Ran GTPase Activating Protein 1 (RANGAP1))

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RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq, Jul 2008].

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Featured RANGAP1 Categories

RANGAP1 抗体

High quality antibodies with extensive validation data.

RANGAP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RANGAP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RANGAP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN519631
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6146681
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN6264633
Quantity 100 μL
Datasheet Datasheet

Recommended RANGAP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1154400
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1154401
Quantity 96 tests
Datasheet Datasheet

Recommended RANGAP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317386
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2730462
Quantity 20 μg
Datasheet Datasheet
Reactivity Schizosaccharomyces pombe
Source Yeast
Validations
Cat. No. ABIN1476641
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RANGAP1 Products

Shitashige, Satow, Honda, Ono, Hirohashi, Yamada: "Regulation of Wnt signaling by the nuclear pore complex." in: Gastroenterology, Vol. 134, Issue 7, pp. 1961-71, 1971.e1-4, (2008) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Yang, Galanis, Witty, Sharrocks: "An extended consensus motif enhances the specificity of substrate modification by SUMO." in: The EMBO journal, Vol. 25, Issue 21, pp. 5083-93, (2006) (PubMed).

Bischoff, Krebber, Kempf, Hermes, Ponstingl: "Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1749-53, (1995) (PubMed).

Synonyms and alternative names related to RANGAP1

Ran GTPase activating protein 1 (RANGAP1), RAN GTPase activating protein 1 (RANGAP1), ran GTPase activating protein 1 (TERG_02084), Ran GTPase activating protein 1 S homeolog (rangap1.S), RAN GTPase activating protein 1 (Rangap1), Ran GTPase activating protein 1 L homeolog (rangap1.L), Ran GAP Rna1 (rna1), Ran GTPase activating protein 1 (Rangap1), Ran GTPase activating protein (RanGAP), RAN GTPase activating protein 1a (rangap1a), ATRANGAP1, C79654, CG9999, CT28175, Dmel\CG9999, dRanGAP, Fug1, fug1, mKIAA1835, Protein rna1, Ran, RANGAP, RanGAP, RanGap, ranGAP, ranGap, rangap, RanGAP1, rangap1, RanGap1, rangap1a, rangap1b, RAN GTPASE-ACTIVATING PROTEIN 1, RAN GTPase activating protein 1, RGP1_DROME, rna1p, Scl, SD, Sd, Sd-RanGAP, Sd-RanGap, zgc:154097

Protein level used designations for RANGAP1

  • ran GTPase-activating protein 1
  • segregation distorter homolog
  • segregation distortion
  • ran GTPase activating protein 1
  • Ran GTPase activating protein 1 b
  • Ran GTPase activating protein 1
  • RAN GTPase activating protein 1
  • RAN GTPase activating protein 1 a
  • CG9999 gene product from transcript CG9999-RA
  • CG9999-PA
  • CG9999-PB
  • CG9999-PC
  • Protein segregation distorter
  • Ran-GTPase activating protein
  • RanGAP-PA
  • RanGAP-PB
  • RanGAP-PC
  • segregation distorter
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