RANBP1 产品
(RAN Binding Protein 1 (RANBP1))
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Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq, Jul 2008].
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Latest Publications for our RANBP1 Products
: "Calpain-dependent disruption of nucleo-cytoplasmic transport in ALS motor neurons." in: Scientific reports, Vol. 7, pp. 39994, (2017) (PubMed).: "Calpain-Dependent Degradation of Nucleoporins Contributes to Motor Neuron Death in a Mouse Model of Chronic Excitotoxicity." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, Issue 36, pp. 8830-8844, (2017) (PubMed).
: "Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport." in: Neuroscience, Vol. 293, pp. 157-70, (2015) (PubMed).
: "NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3." in: Nucleic acids research, Vol. 40, Issue 17, pp. 8484-98, (2012) (PubMed).
: "RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import." in: The Journal of cell biology, Vol. 135, Issue 3, pp. 559-69, (1996) (PubMed).
: "Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1." in: The EMBO journal, Vol. 14, Issue 4, pp. 705-15, (1995) (PubMed).
: "RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4." in: Molecular & general genetics : MGG, Vol. 247, Issue 6, pp. 661-9, (1995) (PubMed).
Synonyms and alternative names related to RANBP1
RAN binding protein 1 S homeolog (ranbp1.S), RAN binding protein 1 L homeolog (ranbp1.L), ran binding protein 1 (PVX_090070), RAN binding protein 1 (GL50803_16969), ran-specific GTPase-activating protein pseudogene (LOC100343953), RAN binding protein 1 (ranbp1), RAN binding protein 1 (RANBP1), RAN binding protein 1 (Ranbp1), hm:zeh1094, HTF9A, Htf9a, MGC64314, wu:fa96a09, wu:fj39g07, zeh1094, zgc:85649Protein level used designations for RANBP1
- RAN binding protein 1
- Ran binding protein 1
- ran binding protein 1
- ran-specific GTPase-activating protein
- HpaII tiny fragments locus 9A
- Htf9-a/RanBP1
- hpaII tiny fragments locus 9a protein
- ran-binding protein 1
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