RAMP1 产品
(Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
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The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq, Jul 2008].
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Featured RAMP1 Categories
RAMP1 抗体
High quality antibodies with extensive validation data.
RAMP1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
RAMP1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAMP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (4)
- (2)
Cat. No.
ABIN731438
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN6146672
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC, IF, ICC, LCI
Validations
- (4)
Cat. No.
ABIN7043595
Quantity
25 μL
Datasheet
Datasheet
Recommended RAMP1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969844
Quantity
96 tests
Datasheet
Datasheet
Recommended RAMP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317365
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317363
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Mammalian Cells
Validations
- (1)
Cat. No.
ABIN7538505
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our RAMP1 Products
: "Excitatory Effects of Calcitonin Gene-Related Peptide (CGRP) on Superficial Sp5C Neurons in Mouse Medullary Slices." in: International journal of molecular sciences, Vol. 22, Issue 7, (2021) (PubMed).: "Chemical phenotypes of intrinsic cardiac neurons in the newborn pig (Sus scrofa domesticus Erxleben, 1777)." in: Journal of morphology, Vol. 283, Issue 1, pp. 51-65, (2021) (PubMed).
: "Alterations in enteric calcitonin gene-related peptide in patients with colonic diverticular disease: CGRP in diverticular disease." in: Autonomic neuroscience : basic & clinical, Vol. 216, pp. 63-71, (2019) (PubMed).
: "Intermedin is upregulated and attenuates renal fibrosis by inhibition of oxidative stress in rats with unilateral ureteral obstruction." in: Nephrology (Carlton, Vic.), (2015) (PubMed).
: "Immobilization contributes to exaggerated neuropeptide signaling, inflammatory changes, and nociceptive sensitization after fracture in rats." in: The journal of pain : official journal of the American Pain Society, Vol. 15, Issue 10, pp. 1033-45, (2014) (PubMed).
: "Keratinocytes express cytokines and nerve growth factor in response to neuropeptide activation of the ERK1/2 and JNK MAPK transcription pathways." in: Regulatory peptides, Vol. 186, pp. 92-103, (2013) (PubMed).
: "Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 42, pp. 16702-7, (2007) (PubMed).
: "Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin." in: The Journal of biological chemistry, Vol. 276, Issue 45, pp. 42182-90, (2001) (PubMed).
Synonyms and alternative names related to RAMP1
receptor activity modifying protein 1 (RAMP1), receptor (G protein-coupled) activity modifying protein 1 (ramp1), receptor (calcitonin) activity modifying protein 1 (Ramp1), receptor activity modifying protein 1 (Ramp1), 9130218E19Rik, MGC147096, RAMP1Protein level used designations for RAMP1
- receptor (calcitonin) activity modifying protein 1
- receptor activity-modifying protein 1
- receptor activity modifying protein 1
- receptor (G protein-coupled) activity modifying protein 1
- CRLR activity-modifying protein 1
- calcitonin receptor-like receptor activity modifying protein 1
- calcitonin-receptor-like receptor activity-modifying protein 1
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