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RAGE 产品

(Advanced Glycosylation End Product-Specific Receptor (AGER))

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The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011].

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Featured RAGE Categories

RAGE 抗体

High quality antibodies with extensive validation data.

RAGE ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RAGE 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RAGE 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7443794
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (6)
Cat. No. ABIN513173
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IP, IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (5)
  • (4)
Cat. No. ABIN725900
Quantity 100 μL
Datasheet Datasheet

Recommended RAGE ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959058
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963197
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959059
Quantity 96 tests
Datasheet Datasheet

Recommended RAGE 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275509
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7273807
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7273806
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our RAGE Products

Aue, Englert, Harrer, Schwiering, Gaab, König, Adams, Schmidtko, Friebe, Groneberg: "NO-sensitive guanylyl cyclase discriminates pericyte-derived interstitial from intra-alveolar myofibroblasts in murine pulmonary fibrosis." in: Respiratory research, Vol. 24, Issue 1, pp. 167, (2023) (PubMed).

Evran, Calis, Akkaya, Baran, Cevik, Katar, Gurevin, Hanimoglu, Hatiboglu, Armutak, Karatas, Kocyigit, Kaynar: "The effect of high mobility group box-1 protein on cerebral edema, blood-brain barrier, oxidative stress and apoptosis in an experimental traumatic brain injury model." in: Brain research bulletin, Vol. 154, pp. 68-80, (2020) (PubMed).

Chen, Lin, Lin, Chen, Yen: "Potential effect of advanced glycation end products (AGEs) on spermatogenesis and sperm quality in rodents." in: Food & function, Vol. 10, Issue 6, pp. 3324-3333, (2019) (PubMed).

Kim, Lee, Kim, Ryu, Chon, Park, Fu, Huh, Lim, Koh, Choi, Hong: "Serum developmental endothelial locus-1 is associated with severity of sepsis in animals and humans." in: Scientific reports, Vol. 9, Issue 1, pp. 13005, (2019) (PubMed).

Oztay, Sancar-Bas, Gezginci-Oktayoglu, Ercin, Bolkent: "Exendin-4 partly ameliorates - hyperglycemia-mediated tissue damage in lungs of streptozotocin-induced diabetic mice." in: Peptides, Vol. 99, pp. 99-107, (2018) (PubMed).

Wu, Zheng, Bai, Xia, Zhang, Guo: "HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma." in: OncoTargets and therapy, Vol. 11, pp. 4501-4510, (2018) (PubMed).

Bouchikh, Zouaidia, Benhaddou, Mahassini, Achir, El Malki: "Expression of receptor for advanced glycation end-products (RAGE) in thymus from myasthenia patients." in: Revue neurologique, Vol. 173, Issue 6, pp. 388-395, (2018) (PubMed).

Yan, Zhu, Zhang, Li, Li, Wang, Leng: "HMGB1-RAGE signaling pathway in pPROM." in: Taiwanese journal of obstetrics & gynecology, Vol. 57, Issue 2, pp. 211-216, (2018) (PubMed).

Qiu, Tang, Wei: "Berberine exerts renoprotective effects by regulating the AGEs-RAGE signaling pathway in mesangial cells during diabetic nephropathy." in: Molecular and cellular endocrinology, Vol. 443, pp. 89-105, (2017) (PubMed).

Zhang, Wang, Xue, Lai, Ji, Jin, Chen: "Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling." in: American journal of translational research, Vol. 9, Issue 1, pp. 115-125, (2017) (PubMed).

Synonyms and alternative names related to RAGE

advanced glycosylation end-product specific receptor (AGER), advanced glycosylation end product-specific receptor (Ager), advanced glycosylation end-product specific receptor (Ager), MAPK/MAK/MRK overlapping kinase (LOC719012), AGER, RAGE

Protein level used designations for RAGE

  • RAGE isoform NtRAGE-delta
  • RAGE isoform sRAGE-delta
  • advanced glycation end-products receptor
  • receptor for advanced glycosylation end products
  • advanced glycosylation end product-specific receptor variant 2
  • advanced glycosylation end product-specific receptor variant 3
  • advanced glycosylation end product-specific receptor variant 4
  • advanced glycosylation end product-specific receptor variant 5
  • advanced glycosylation end product-specific receptor variant 1
  • advanced glycosylation end product-specific receptor variant 6
  • advanced glycosylation end product-specific receptor variant 7
  • advanced glycosylation end product-specific receptor variant 8
  • RAGE/AGER
  • advanced glycation end product receptor
  • advanced glycosylation end product-specific receptor
  • MAPK/MAK/MRK overlapping kinase
  • renal tumor antigen
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