RAG2 产品
(Recombination Activating Gene 2 (RAG2))
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This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. [provided by RefSeq, Jul 2008].
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Featured RAG2 Categories
RAG2 抗体
High quality antibodies with extensive validation data.
RAG2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
RAG2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAG2 抗体
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Reactivity
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Datasheet
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Cat. No.
ABIN2856698
Quantity
100 μL
Datasheet
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Cat. No.
ABIN950151
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Cat. No.
ABIN519621
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Recommended RAG2 ELISA试剂盒
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ABIN6969857
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96 tests
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ABIN1166582
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Goat
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Recommended RAG2 蛋白
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ABIN1317323
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10 μg
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Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094940
Quantity
1 mg
Datasheet
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Reactivity
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ABIN3133308
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Latest Publications for our RAG2 Products
: "Joining mutants of RAG1 and RAG2 that demonstrate impaired interactions with the coding-end DNA." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38360-8, (2004) (PubMed).Synonyms and alternative names related to RAG2
recombination activating 2 (RAG2), recombination activating gene 2 (RAG2), recombination activating gene 2 (Rag2), recombination activating 2 (Rag2), recombination activating gene 2 (rag2), recombination activating gene 2 S homeolog (rag2.S), RAG-2, Rag-2, rag-2, zgc:136743Protein level used designations for RAG2
- recombination activating gene 2
- recombination activating protein 2
- V(D)J recombination-activating protein 2-like
- V(D)J recombination-activating protein 2
- recombinase activating gene 2
- v(D)J recombination-activating protein 2
- RAG-2
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