RAF1 抗体
(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].
recommended
RAF1 抗体 (AA 31-130) (ABIN733208)
RAF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
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Popular RAF1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (2)
- (1)
Cat. No.
ABIN733208
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (1)
- (7)
Cat. No.
ABIN3020713
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi, PLA
Validations
- (7)
Cat. No.
ABIN519618
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN969560
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN6256385
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (1)
- (4)
Cat. No.
ABIN6256220
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, IP
Validations
- (4)
Cat. No.
ABIN7167060
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7254803
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
- (3)
Cat. No.
ABIN6255230
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (4)
Cat. No.
ABIN3019551
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS, EIA
Validations
- (5)
Cat. No.
ABIN1108823
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6256250
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN6243077
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7127737
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), FACS
Validations
- (4)
Cat. No.
ABIN392261
Quantity
400 μL
Datasheet
Datasheet
Latest Publications for our RAF1 抗体
: "Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer." in: Cancer medicine, Vol. 7, Issue 4, pp. 1546-1559, (2018) (PubMed).: "EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer." in: Molecular medicine reports, Vol. 17, Issue 6, pp. 7875-7885, (2018) (PubMed).
: "Wogonoside induces depalmitoylation and translocation of PLSCR1 and N-RAS in primary acute myeloid leukaemia cells." in: Journal of cellular and molecular medicine, Vol. 22, Issue 4, pp. 2117-2130, (2018) (PubMed).
: "Hypoxic postconditioning attenuates apoptosis via inactivation of adenosine A2a receptor through NDRG3-Raf-ERK pathway." in: Biochemical and biophysical research communications, Vol. 491, Issue 2, pp. 277-284, (2017) (PubMed).
: "Type II cGMP-dependent protein kinase negatively regulates fibroblast growth factor signaling by phosphorylating Raf-1 at serine 43 in rat chondrosarcoma cells." in: Biochemical and biophysical research communications, Vol. 483, Issue 1, pp. 82-87, (2017) (PubMed).
: "Zika virus cell tropism in the developing human brain and inhibition by azithromycin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 50, pp. 14408-14413, (2016) (PubMed).
: "The role of Dectin-1/Raf-1 signal cascade in innate immune of human corneal epithelial cells against Aspergillus fumigatus infection." in: International journal of ophthalmology, Vol. 9, Issue 10, pp. 1371-1375, (2016) (PubMed).
: "Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling." in: eLife, Vol. 5, (2016) (PubMed).
: "Bone marrow mononuclear cell transplantation promotes therapeutic angiogenesis via upregulation of the VEGF-VEGFR2 signaling pathway in a rat model of vascular dementia." in: Behavioural brain research, Vol. 265, pp. 171-80, (2014) (PubMed).
: "Regulation of integrin ?V subunit expression by sulfatide in hepatocellular carcinoma cells." in: Journal of lipid research, Vol. 54, Issue 4, pp. 936-52, (2013) (PubMed).
Aliases for RAF1 抗体
Raf-1 proto-oncogene, serine/threonine kinase (RAF1) 抗体Raf-1 proto-oncogene, serine/threonine kinase (Raf1) 抗体
Raf-1 proto-oncogene, serine/threonine kinase a (raf1a) 抗体
Raf-1 proto-oncogene, serine/threonine kinase (raf1) 抗体
v-raf-leukemia viral oncogene 1 (Raf1) 抗体
Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S) 抗体
6430402F14Rik 抗体
AA990557 抗体
BB129353 抗体
c-Raf 抗体
c-raf 抗体
CRAF 抗体
craf 抗体
cRaf 抗体
Craf1 抗体
D830050J10Rik 抗体
NS5 抗体
raf 抗体
Raf-1 抗体
raf1 抗体
RAF1 抗体
v-Raf 抗体
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