RAD9A 产品
(RAD9 Homolog A (S. Pombe) (RAD9A))
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This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Featured RAD9A Categories
Recommended RAD9A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN3022652
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IF, ICC
Validations
- (5)
Cat. No.
ABIN2857053
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN1500581
Quantity
100 μL
Datasheet
Datasheet
Recommended RAD9A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6206964
Quantity
96 tests
Datasheet
Datasheet
Recommended RAD9A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317298
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094931
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137560
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RAD9A Products
: "TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint." in: BMC molecular biology, Vol. 17, pp. 3, (2016) (PubMed).: "Over expression of hRad9 protein correlates with reduced chemosensitivity in breast cancer with administration of neoadjuvant chemotherapy." in: Scientific reports, Vol. 4, pp. 7548, (2015) (PubMed).
: "Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit." in: PLoS ONE, Vol. 8, Issue 12, pp. e85859, (2013) (PubMed).
: "Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy." in: Genes & cancer, Vol. 4, Issue 1-2, pp. 39-53, (2013) (PubMed).
: "UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway." in: Journal of cell science, Vol. 126, Issue Pt 9, pp. 1923-30, (2013) (PubMed).
: "Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins." in: Journal of virology, Vol. 87, Issue 1, pp. 531-42, (2012) (PubMed).
: "Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1." in: DNA repair, Vol. 9, Issue 5, pp. 478-87, (2010) (PubMed).
: "Metnase promotes restart and repair of stalled and collapsed replication forks." in: Nucleic acids research, Vol. 38, Issue 17, pp. 5681-91, (2010) (PubMed).
: "Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery." in: Human molecular genetics, Vol. 20, Issue 1, pp. 126-40, (2010) (PubMed).
: "ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage." in: Journal of cell science, Vol. 121, Issue Pt 23, pp. 3933-40, (2008) (PubMed).
Synonyms and alternative names related to RAD9A
RAD9 checkpoint clamp component A (RAD9A), RAD9 checkpoint clamp component A (Rad9a), RAD9 checkpoint clamp component A (rad9a), RAD9 checkpoint clamp component B (rad9b), RAD9 checkpoint clamp component A L homeolog (rad9a.L), MGC89062, RAD9, Rad9, rad9, rad9a, XRad9Protein level used designations for RAD9A
- DNA repair exonuclease rad9 homolog A
- cell cycle checkpoint control protein RAD9A
- hRAD9
- RAD9 homolog A (S. pombe)
- cell cycle checkpoint control protein RAD9A-like
- Rad9-like protein
- mRAD9
- RAD9 homolog A
- rCG47324-like
- PCNA-like DNA checkpoint protein Rad9
- RAD9 checkpoint clamp component A L homeolog
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