RAD51 Homolog B 产品
(RAD51 Homolog B (Rad51B))
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The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011].
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Featured RAD51 Homolog B Categories
RAD51 Homolog B 抗体
High quality antibodies with extensive validation data.
RAD51 Homolog B 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAD51 Homolog B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6259179
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (4)
Cat. No.
ABIN2787357
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Human, Monkey, Mouse
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN6746527
Quantity
100 μL
Datasheet
Datasheet
Recommended RAD51 Homolog B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232260
Quantity
96 tests
Datasheet
Datasheet
Recommended RAD51 Homolog B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317287
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2131471
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094872
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RAD51 Homolog B Products
: "BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage." in: DNA repair, Vol. 12, Issue 4, pp. 306-11, (2013) (PubMed).: "S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 20 Suppl 2, Issue 6, pp. S513-26, (2010) (PubMed).
: "Dysfunctional homologous recombination mediates genomic instability and progression in myeloma." in: Blood, Vol. 113, Issue 10, pp. 2290-7, (2009) (PubMed).
: "Differential regulation of short- and long-tract gene conversion between sister chromatids by Rad51C." in: Molecular and cellular biology, Vol. 26, Issue 21, pp. 8075-86, (2006) (PubMed).
: "Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells." in: Oncogene, Vol. 21, Issue 25, pp. 4065-9, (2002) (PubMed).
: "Identification and purification of two distinct complexes containing the five RAD51 paralogs." in: Genes & development, Vol. 15, Issue 24, pp. 3296-307, (2001) (PubMed).
: "Identification of a novel human RAD51 homolog, RAD51B." in: Genomics, Vol. 46, Issue 3, pp. 476-9, (1998) (PubMed).
Synonyms and alternative names related to RAD51 Homolog B
RAD51 paralog B (RAD51B), RAD51 paralog B (Rad51b), DNA repair (Rad51) family protein (RAD51B), Rad51 DNA recombinase 2 (RAD51B), RAD51 paralog B (rad51b), AI553500, ATRAD51B, mREC2, R51H2, RAD51L1, Rad51l1, rad51l1, REC2, RGD1560681, T17D12.12, T17D12_12, wu:fd07f04, zgc:56581Protein level used designations for RAD51 Homolog B
- DNA repair protein RAD51 homolog 2
- RAD51 homolog B
- RecA-like protein
- recombination repair protein
- RAD51-like 1
- RAD51-like protein 1
- Rad51 DNA recombinase 2
- DKEYP-88E3.2
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