RAD51 Homolog 产品
(RAD51 Homolog (RAD51))
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The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].
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Recommended RAD51 Homolog 抗体
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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, IP, WB, ICC
Validations
- (2)
Cat. No.
ABIN7430222
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IP, WB, IF/ICC
Validations
Cat. No.
ABIN6336962
Quantity
1 mL
Datasheet
Datasheet
Recommended RAD51 Homolog ELISA试剂盒
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Reactivity
Analytical Method
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Quantity
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Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959042
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5658348
Quantity
96 tests
Datasheet
Datasheet
Recommended RAD51 Homolog 蛋白
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Reactivity
Source
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Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7386428
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RAD51 Homolog Products
: "Induction of apoptosis and modulation of homologous recombination DNA repair pathway in prostate cancer cells by the combination of AZD2461 and valproic acid." in: EXCLI journal, Vol. 18, pp. 485-498, (2019) (PubMed).Synonyms and alternative names related to RAD51 Homolog
RAD51 recombinase (RAD51), BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECAProtein level used designations for RAD51 Homolog
- BRCA1/BRCA2-containing complex, subunit 5
- DNA repair protein RAD51 homolog 1
- RAD51 homolog A
- RecA, E. coli, homolog of
- RecA-like protein
- recombination protein A
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