RAD23B 抗体
(RAD23 Homolog B (RAD23B))
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011].
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recommended
RAD23B 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H7 unconjugated
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Datasheet
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Latest Publications for our RAD23B 抗体
: "Phase I trial of induction histone deacetylase and proteasome inhibition followed by surgery in non-small-cell lung cancer." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 7, Issue 11, pp. 1683-90, (2012) (PubMed).: "MicroRNA regulation of DNA repair gene expression in hypoxic stress." in: Cancer research, Vol. 69, Issue 3, pp. 1221-9, (2009) (PubMed).
: "Scanning the human proteome for calmodulin-binding proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 17, pp. 5969-74, (2005) (PubMed).
: "Expression of a novel RAD23B mRNA splice variant in the human testis." in: Journal of andrology, Vol. 25, Issue 3, pp. 363-8, (2004) (PubMed).
: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).
: "Structural determinants for the binding of ubiquitin-like domains to the proteasome." in: The EMBO journal, Vol. 22, Issue 18, pp. 4634-45, (2003) (PubMed).
: "A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein." in: Genes & development, Vol. 17, Issue 13, pp. 1630-45, (2003) (PubMed).
: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
: "Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway." in: Life sciences, Vol. 71, Issue 19, pp. 2267-77, (2002) (PubMed).
: "Involvement of rhp23, a Schizosaccharomyces pombe homolog of the human HHR23A and Saccharomyces cerevisiae RAD23 nucleotide excision repair genes, in cell cycle control and protein ubiquitination." in: Nucleic acids research, Vol. 30, Issue 2, pp. 581-91, (2002) (PubMed).
Aliases for RAD23B 抗体
RAD23 homolog B, nucleotide excision repair protein (RAD23B) 抗体RAD23 homolog B, nucleotide excision repair protein (Rad23b) 抗体
UV excision repair protein RAD23 homolog B (rd23b) 抗体
RAD23 homolog B, nucleotide excision repair protein (rad23b) 抗体
RAD23 homolog B, nucleotide excision repair protein S homeolog (rad23b.S) 抗体
0610007D13Rik 抗体
AV001138 抗体
HHR23B 抗体
HR23B 抗体
MGC107846 抗体
mHR23B 抗体
P58 抗体
p58 抗体
zgc:65951 抗体
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