RAD17 抗体
(RAD17)
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2008].
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RAD17 抗体 by 适用
Find RAD17 抗体 for a variety of species such as anti-Human RAD17, anti-Mouse RAD17, anti-Rat RAD17. The species listed below are among those available. Click on a link to go to the corresponding products.
RAD17 抗体 by 抗体来源
Find RAD17 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
RAD17 抗体 by 克隆形成能力
Find available monoclonal or polyclonal RAD17 抗体. Click on a link to go to the corresponding products.
RAD17 抗体 by 克隆
Find RAD17 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular RAD17 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN519598
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN562564
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN6146626
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7147264
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6264606
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Mouse, Pig, Rat
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN2779300
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7301194
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN1532259
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IP, IHC (p)
Validations
- (3)
Cat. No.
ABIN492574
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7182545
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Dog, Hamster, Human, Monkey, Pig
Application
WB
Validations
- (1)
Cat. No.
ABIN6742192
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF
Validations
- (1)
Cat. No.
ABIN3186650
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN3183071
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN3182190
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN519597
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our RAD17 抗体
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).: "Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability." in: The EMBO journal, Vol. 31, Issue 4, pp. 908-18, (2012) (PubMed).
: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." in: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).
: "Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress." in: Genes & development, Vol. 21, Issue 24, pp. 3331-41, (2007) (PubMed).
: "Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling." in: The EMBO journal, Vol. 23, Issue 23, pp. 4660-9, (2004) (PubMed).
: "ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses." in: Nature, Vol. 411, Issue 6840, pp. 969-74, (2001) (PubMed).
: "Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 23, pp. 13102-7, (2001) (PubMed).
: "hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation." in: Oncogene, Vol. 18, Issue 9, pp. 1689-99, (1999) (PubMed).
Aliases for RAD17 抗体
RAD17 checkpoint clamp loader component (RAD17) 抗体RAD17 checkpoint clamp loader component (rad17) 抗体
Rad17p (RAD17) 抗体
RADIATION SENSITIVE 17 (ATRAD17) 抗体
RAD17 checkpoint clamp loader component (Rad17) 抗体
9430035O09Rik 抗体
CCYC 抗体
HRAD17 抗体
K2A18.21 抗体
K2A18_21 抗体
MmRad24 抗体
R24L 抗体
RAD17 抗体
RAD17SP 抗体
RAD24 抗体
RADIATION SENSITIVE 17 抗体
zgc:91969 抗体
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