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RABGEF1 产品

(RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

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RABGEF1 forms a complex with rabaptin-5 (RABPT5\; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A\; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010].

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Featured RABGEF1 Categories

RABGEF1 抗体

High quality antibodies with extensive validation data.

RABGEF1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RABGEF1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RABGEF1 抗体

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Reactivity
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Reactivity Human
Application ELISA, IHC
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Cat. No. ABIN7167001
Quantity 100 μg
Datasheet Datasheet
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Application WB
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Cat. No. ABIN525977
Quantity 50 μg
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Application WB
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  • (1)
Cat. No. ABIN6743794
Quantity 100 μL
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Recommended RABGEF1 ELISA试剂盒

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Reactivity Human
Analytical Method
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Cat. No. ABIN1154281
Quantity 96 tests
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Reactivity Mouse
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Cat. No. ABIN1154282
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Reactivity Cow
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Cat. No. ABIN1154280
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Recommended RABGEF1 蛋白

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Quantity 10 μg
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Cat. No. ABIN3130347
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Cat. No. ABIN5711903
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Latest Publications for our RABGEF1 Products

Yamano, Wang, Sarraf, Münch, Kikuchi, Noda, Hizukuri, Kanemaki, Harper, Tanaka, Matsuda, Youle: "Endosomal Rab cycles regulate Parkin-mediated mitophagy." in: eLife, Vol. 7, (2018) (PubMed).

Lucitti, Sealock, Buckley, Zhang, Xiao, Dudley, Faber: "Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke." in: Stroke, Vol. 47, Issue 12, pp. 3022-3031, (2016) (PubMed).

Saito, Murai, Kajiho, Kontani, Kurosu, Katada: "A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5." in: The Journal of biological chemistry, Vol. 277, Issue 5, pp. 3412-8, (2002) (PubMed).

Rubino, Miaczynska, Lippé, Zerial: "Selective membrane recruitment of EEA1 suggests a role in directional transport of clathrin-coated vesicles to early endosomes." in: The Journal of biological chemistry, Vol. 275, Issue 6, pp. 3745-8, (2000) (PubMed).

Horiuchi, Lippé, McBride, Rubino, Woodman, Stenmark, Rybin, Wilm, Ashman, Mann, Zerial: "A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function." in: Cell, Vol. 90, Issue 6, pp. 1149-59, (1997) (PubMed).

Synonyms and alternative names related to RABGEF1

RAB guanine nucleotide exchange factor (GEF) 1 (Rabgef1), RAB guanine nucleotide exchange factor 1 (Rabgef1), RAB guanine nucleotide exchange factor 1 (RABGEF1), RAB guanine nucleotide exchange factor (GEF) 1 L homeolog (rabgef1.L), Rab5ef, rabex-5, Rabex5, RABEX5, rabgef1, Rin2

Protein level used designations for RABGEF1

  • Rab5 exchange factor
  • Ras negative regulator Rabex-5
  • Ras negative regulator Rabex-5/Rin2
  • rab5 GDP/GTP exchange factor
  • rabex-5
  • RAP1
  • rabaptin-5-associated exchange factor for Rab5
  • Rab5 guanine nucleotide exchange factor Rabex-5
  • RAB guanine nucleotide exchange factor (GEF) 1
  • Rab5 GDP/GTP exchange factor
  • BTB/POZ domain-containing protein KCTD7
  • RAB guanine nucleotide exchange factor (GEF) 1 L homeolog
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