RAB8A 抗体
(RAB8A, Member RAS Oncogene Family (RAB8A))
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008].
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RAB8A 抗体 by 标记
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Popular RAB8A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN561805
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5542342
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (2)
- (4)
Cat. No.
ABIN1881723
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (2)
Cat. No.
ABIN715316
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
Cat. No.
ABIN4913414
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7239401
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Avian, Cat, Chicken, Cow, Dog, Donkey, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB, IHC (p), IF, IHC (fro)
Validations
- (2)
Cat. No.
ABIN6254181
Quantity
600 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN3042554
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Mouse, Pig, Rat, Sheep, Zebrafish (Danio rerio)
Application
WB
Validations
- (3)
Cat. No.
ABIN2792290
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS
Validations
- (3)
Cat. No.
ABIN3003984
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN2476294
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN238664
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Horse, Human, Monkey, Mouse, Pig, Rat, Sheep, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6741500
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN2578046
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Human, Mouse, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN926981
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our RAB8A 抗体
: "Transcription factor EB‑mediated autophagy promotes dermal fibroblast differentiation and collagen production by regulating endoplasmic reticulum stress and autophagy‑dependent secretion." in: International journal of molecular medicine, Vol. 47, Issue 2, pp. 547-560, (2021) (PubMed).: "Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3." in: The Journal of cell biology, Vol. 211, Issue 3, pp. 587-604, (2015) (PubMed).
: "Drebrin E depletion in human intestinal epithelial cells mimics Rab8a loss of function." in: Human molecular genetics, Vol. 23, Issue 11, pp. 2834-46, (2014) (PubMed).
: "Levels of Rabs and WAVE family proteins associated with translocation of GLUT4 to the cell surface in endometria from hyperinsulinemic PCOS women." in: Human reproduction (Oxford, England), Vol. 25, Issue 11, pp. 2870-7, (2010) (PubMed).
: "Functional dissection of Rab GTPases involved in primary cilium formation." in: The Journal of cell biology, Vol. 178, Issue 3, pp. 363-9, (2007) (PubMed).
: "Rab27a: A key to melanosome transport in human melanocytes." in: The Journal of cell biology, Vol. 152, Issue 4, pp. 843-50, (2001) (PubMed).
: "Rab27a regulates the peripheral distribution of melanosomes in melanocytes." in: The Journal of cell biology, Vol. 152, Issue 4, pp. 795-808, (2001) (PubMed).
: "Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation." in: Molecular biology of the cell, Vol. 11, Issue 1, pp. 393-412, (2000) (PubMed).
: "Construction of a human full-length cDNA bank." in: Gene, Vol. 150, Issue 2, pp. 243-50, (1995) (PubMed).
: "Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line." in: Molecular and cellular biology, Vol. 10, Issue 12, pp. 6578-85, (1991) (PubMed).
Aliases for RAB8A 抗体
rab8A protein (rab8A) 抗体Rab GTPase (rab8A) 抗体
RAB8A, member RAS oncogene family (RAB8A) 抗体
RAB8A, member RAS oncogene family (rab8a) 抗体
RAB8A, member RAS oncogene family S homeolog (rab8a.S) 抗体
RAB8A, member RAS oncogene family (Rab8a) 抗体
AA409338 抗体
c-mel 抗体
DDBDRAFT_0206521 抗体
DDBDRAFT_0214885 抗体
DDB_0206521 抗体
DDB_0214885 抗体
HSH2D 抗体
mel 抗体
MEL 抗体
Mel 抗体
rab8 抗体
RAB8 抗体
Rab8 抗体
rab8A 抗体
zgc:162699 抗体
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