RAB7B 抗体
(RAB7B, Member RAS Oncogene Family (RAB7B))
Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway (By similarity).
recommended
recommended
recommended
RAB7B 抗体 by 适用
Find RAB7B 抗体 for a variety of species such as anti-Human RAB7B, anti-Mouse RAB7B, anti-Rat RAB7B. The species listed below are among those available. Click on a link to go to the corresponding products.
RAB7B 抗体 by 应用范围
Find RAB7B 抗体 validated for a specific application such as WB, ELISA, IP, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
RAB7B 抗体 by 抗体来源
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RAB7B 抗体 by 抗原表位
Find RAB7B 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
RAB7B 抗体 by 克隆形成能力
Find available monoclonal or polyclonal RAB7B 抗体. Click on a link to go to the corresponding products.
RAB7B 抗体 by 克隆
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RAB7B 抗体 by 标记
Find RAB7B 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular RAB7B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (6)
- (6)
Cat. No.
ABIN567027
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
- (1)
Cat. No.
ABIN1881722
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN531619
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN531617
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7167381
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN567026
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN3028970
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7167384
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7167382
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
Cat. No.
ABIN7118233
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
Cat. No.
ABIN7136115
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
Cat. No.
ABIN1805468
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
Cat. No.
ABIN2578045
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
Cat. No.
ABIN1928829
Quantity
200 μL
Datasheet
Datasheet
Latest Publications for our RAB7B 抗体
: "Rab7a regulates cell migration through Rac1 and vimentin." in: Biochimica et biophysica acta, Vol. 1864, Issue 2, pp. 367-381, (2016) (PubMed).: "A novel interaction between Rab7b and actomyosin reveals a dual role in intracellular transport and cell migration." in: Journal of cell science, Vol. 127, Issue 22, pp. 4927-39, (2014) (PubMed).
: "Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells." in: Molecular biology of the cell, Vol. 22, Issue 10, pp. 1699-715, (2011) (PubMed).
: "GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation." in: Journal of neurochemistry, Vol. 115, Issue 2, pp. 423-37, (2010) (PubMed).
: "Rab7b controls trafficking from endosomes to the TGN." in: Journal of cell science, Vol. 123, Issue Pt 9, pp. 1480-91, (2010) (PubMed).
: "SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery." in: Molecular biology of the cell, Vol. 20, Issue 4, pp. 1223-40, (2009) (PubMed).
: "Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease." in: Journal of neuropathology and experimental neurology, Vol. 68, Issue 9, pp. 994-1005, (2009) (PubMed).
: "Rab7b, a novel lysosome-associated small GTPase, is involved in monocytic differentiation of human acute promyelocytic leukemia cells." in: Biochemical and biophysical research communications, Vol. 318, Issue 3, pp. 792-9, (2004) (PubMed).
Aliases for RAB7B 抗体
Rab7b, member RAS oncogene family (Rab7b) 抗体rab7B protein (rab7B) 抗体
RAB7B, member RAS oncogene family (RAB7B) 抗体
RAB7B, member RAS oncogene family S homeolog (rab7b.S) 抗体
RAB7B, member RAS oncogene family (rab7b) 抗体
RAB7B, member RAS oncogene family (Rab7b) 抗体
RAB7 抗体
RAB7B 抗体
Rab7b 抗体
RGD1562617 抗体
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