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QPCT 产品

(Glutaminyl-Peptide Cyclotransferase (QPCT))

Categories

This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008].

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Featured QPCT Categories

QPCT 抗体

High quality antibodies with extensive validation data.

QPCT ELISA试剂盒

Reliable ELISA kits for a wide range of species.

QPCT 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended QPCT 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN525429
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN2565834
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7436441
Quantity 100 μL
Datasheet Datasheet

Recommended QPCT ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956187
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1134945
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1134943
Quantity 96 tests
Datasheet Datasheet

Recommended QPCT 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317002
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317000
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7399268
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our QPCT Products

Chokhawala, Roche, Kim, Atreya, Vegesna, Dana, Blanch, Clark: "Mutagenesis of Trichoderma reesei endoglucanase I: impact of expression host on activity and stability at elevated temperatures." in: BMC biotechnology, Vol. 15, pp. 11, (2015) (PubMed).

Guo, He, Liu, Zhang, Lv, Zeng, Gu, Wu: "Identification and Epigenetic Analysis of a Maternally Imprinted Gene Qpct." in: Molecules and cells, Vol. 38, Issue 10, pp. 859-65, (2015) (PubMed).

Morawski, Schilling, Kreuzberger, Waniek, Jäger, Koch, Cynis, Kehlen, Arendt, Hartlage-Rübsamen, Demuth, Roßner: "Glutaminyl cyclase in human cortex: correlation with (pGlu)-amyloid-? load and cognitive decline in Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 39, Issue 2, pp. 385-400, (2014) (PubMed).

Dana, Dotson-Fagerstrom, Roche, Kal, Chokhawala, Blanch, Clark: "The importance of pyroglutamate in cellulase Cel7A." in: Biotechnology and bioengineering, Vol. 111, Issue 4, pp. 842-7, (2014) (PubMed).

Valenti, Bolognin, Zanatta, Donatelli, Innamorati, Pampanin, Zanusso, Zatta, Dalle Carbonare: "Increased glutaminyl cyclase expression in peripheral blood of Alzheimer's disease patients." in: Journal of Alzheimer's disease : JAD, Vol. 34, Issue 1, pp. 263-71, (2013) (PubMed).

Chen, Huang, Kuo, Lo, Lee, Wang: "Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins." in: The Biochemical journal, Vol. 442, Issue 2, pp. 403-12, (2012) (PubMed).

Hartlage-Rübsamen, Morawski, Waniek, Jäger, Zeitschel, Koch, Cynis, Schilling, Schliebs, Demuth, Rossner: "Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-A? deposits in hippocampus via distinct cellular mechanisms." in: Acta neuropathologica, Vol. 121, Issue 6, pp. 705-19, (2011) (PubMed).

Morawski, Hartlage-Rübsamen, Jäger, Waniek, Schilling, Schwab, McGeer, Arendt, Demuth, Rossner: "Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease." in: Acta neuropathologica, Vol. 120, Issue 2, pp. 195-207, (2010) (PubMed).

Synonyms and alternative names related to QPCT

glutaminyl-peptide cyclotransferase (QPCT), glutaminyl-peptide cyclotransferase (glutaminyl cyclase) (Qpct), glutaminyl-peptide cyclotransferase (M6_Spy0443), glutaminyl-peptide cyclotransferase (M5005_Spy_0416), glutaminyl-peptide cyclotransferase (M28_Spy0404), glutaminyl-peptide cyclotransferase (CJA_2408), glutaminyl-peptide cyclotransferase (CCNA_02733), glutaminyl-peptide cyclotransferase (Tsp_03182), glutaminyl-peptide cyclotransferase (Qpct), glutaminyl-peptide cyclotransferase L homeolog (qpct.L), 5730422A13Rik, GCT, QC, QPCT, qpct, Qpctl1, RGD1562284, sQC

Protein level used designations for QPCT

  • EC
  • glutaminyl cyclase
  • glutaminyl-tRNA cyclotransferase
  • glutamyl cyclase
  • glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
  • QC
  • glutaminyl-peptide cyclotransferase
  • glutaminyl-peptide cyclotransferase-like 1
  • glutaminyl-peptide cyclotransferase L homeolog
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