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PYCARD 蛋白

(PYD and CARD Domain Containing (PYCARD))

This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

recommended

PYCARD Protein (AA 1-149) (GST tag) (ABIN1316968)

PYCARD 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

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recommended

PYCARD Protein (AA 1-193) (His tag) (ABIN7565022)

custom-made PYCARD 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris Page, Western Blot WB, SDS

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recommended

PYCARD Protein (AA 1-195) (His tag) (ABIN7552364)

custom-made PYCARD 宿主: 人宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris Page, Western Blot WB, SDS

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PYCARD 蛋白 by Grade

Find PYCARD 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PYCARD 蛋白 by Origin

Find PYCARD 蛋白 for a variety of species such as anti-Human PYCARD, anti-Mouse PYCARD, anti-Cow PYCARD. The species listed below are among those available. Click on a link to go to the corresponding products.

PYCARD 蛋白 by Source

Here you will find PYCARD 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PYCARD 蛋白 by 蛋白类型

Here you can find PYCARD 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

PYCARD 蛋白 by 应用范围

Find PYCARD 蛋白 validated for a specific application such as ELISA, WB, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PYCARD 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

PYCARD Protein (AA 1-149) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1316968

Quantity 10 μg

Datasheet Datasheet

PYCARD Protein (AA 1-193) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7565022

Quantity 1 mg

Datasheet Datasheet

PYCARD Protein (AA 1-195) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7552364

Quantity 1 mg

Datasheet Datasheet

PYCARD Protein (AA 1-195) (Strep Tag)

Reactivity Human

Source Cell-free protein synthesis (CFPS)

Validations

Cat. No. ABIN3089316

Quantity 1 mg

Datasheet Datasheet

PYCARD Protein (AA 1-193) (Strep Tag)

Reactivity Mouse

Source Cell-free protein synthesis (CFPS)

Validations

Cat. No. ABIN3137154

Quantity 1 mg

Datasheet Datasheet

PYCARD Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2730218

Quantity 20 μg

Datasheet Datasheet

PYCARD Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2713166

Quantity 20 μg

Datasheet Datasheet

PYCARD Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2713165

Quantity 20 μg

Datasheet Datasheet

PYCARD Protein (AA 1-195) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1636486

Quantity 1 mg

Datasheet Datasheet

PYCARD Protein (AA 1-203) (His tag)

Reactivity Zebrafish (Danio rerio)

Source Yeast

Validations

Cat. No. ABIN1646663

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our PYCARD 蛋白

Shi, Wang, Li, Zhan, Tang, Fina, Su, Pratt, Bu, Hildebrand, Lyon, Scott, Quan, Sun, Russell, Arnett, Jurek, Chen, Kravchenko, Mathison, Moresco, Monson, Ulevitch, Beutler: "NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component." in: Nature immunology, Vol. 17, Issue 3, pp. 250-8, (2016) (PubMed).

Aliases for PYCARD 蛋白

PYD and CARD domain containing (PYCARD) 蛋白
PYD and CARD domain containing (Pycard) 蛋白
PYD and CARD domain containing (pycard) 蛋白
9130417A21Rik 蛋白
ASC 蛋白
Asc 蛋白
asc1 蛋白
CARD5 蛋白
masc 蛋白
TMS 蛋白
TMS-1 蛋白
TMS1 蛋白
TNS1 蛋白
zAsc 蛋白
zgc:109874 蛋白

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PYCARD 蛋白 by Grade

PYCARD 蛋白 by Origin

PYCARD 蛋白 by Source

PYCARD 蛋白 by 蛋白类型

PYCARD 蛋白 by 应用范围

Popular PYCARD 蛋白

Latest Publications for our PYCARD 蛋白

Aliases for PYCARD 蛋白

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