PYCARD 抗体
(PYD and CARD Domain Containing (PYCARD))
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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PYCARD 抗体 by Grade
Find PYCARD 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
PYCARD 抗体 by 适用
Find PYCARD 抗体 for a variety of species such as anti-Human PYCARD, anti-Rat PYCARD, anti-Mouse PYCARD. The species listed below are among those available. Click on a link to go to the corresponding products.
PYCARD 抗体 by 应用范围
Find PYCARD 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
PYCARD 抗体 by 抗体来源
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PYCARD 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PYCARD 抗体. Click on a link to go to the corresponding products.
PYCARD 抗体 by 克隆
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PYCARD 抗体 by 标记
Find PYCARD 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF
Validations
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
ABIN184674
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, FACS, ICC
Validations
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Cat. No.
ABIN5542580
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IF
Validations
- (5)
Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
IHC, IF
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
- (3)
Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IF, IHC (p), ICC, IHC (fro)
Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IF, IHC (p)
Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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- (1)
Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
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Quantity
200 μL
Datasheet
Datasheet
Latest Publications for our PYCARD 抗体
: "PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse." in: Ecotoxicology and environmental safety, Vol. 169, pp. 551-563, (2019) (PubMed).: "AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model." in: Life sciences, Vol. 221, pp. 249-258, (2019) (PubMed).
: "Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry." in: Frontiers in immunology, Vol. 10, pp. 1284, (2019) (PubMed).
: "NLRP3 inflammasome activation in platelets in response to sepsis." in: Physiological reports, Vol. 7, Issue 9, pp. e14073, (2019) (PubMed).
: "Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3-mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting apoptosis." in: European journal of pharmacology, Vol. 835, pp. 82-93, (2018) (PubMed).
: "Oral Administration of Compound Probiotics Ameliorates HFD-Induced Gut Microbe Dysbiosis and Chronic Metabolic Inflammation via the G Protein-Coupled Receptor 43 in Non-alcoholic Fatty Liver Disease ..." in: Probiotics and antimicrobial proteins, (2018) (PubMed).
: "S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking." in: Cell reports, Vol. 22, Issue 9, pp. 2431-2441, (2018) (PubMed).
: "NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media." in: Acta oto-laryngologica, Vol. 138, Issue 12, pp. 1061-1065, (2018) (PubMed).
: "Actin polymerization plays a significant role in asbestos-induced inflammasome activation in mesothelial cells in vitro." in: Histochemistry and cell biology, Vol. 147, Issue 5, pp. 595-604, (2018) (PubMed).
: "Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis." in: Journal of virology, Vol. 91, Issue 24, (2017) (PubMed).
Aliases for PYCARD 抗体
PYD and CARD domain containing (PYCARD) 抗体PYD and CARD domain containing (Pycard) 抗体
PYD and CARD domain containing (pycard) 抗体
9130417A21Rik 抗体
ASC 抗体
Asc 抗体
asc1 抗体
CARD5 抗体
masc 抗体
TMS 抗体
TMS-1 抗体
TMS1 抗体
TNS1 抗体
zAsc 抗体
zgc:109874 抗体
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