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PUMA 蛋白

(BCL2 Binding Component 3 (BBC3))
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011].
PUMA Protein (AA 141-261) (His-IF2DI Tag) PUMA Protein (AA 141-261) (His-IF2DI Tag) PUMA Protein (AA 141-261) (His-IF2DI Tag) (ABIN7121980)

BBC3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA

PUMA Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) PUMA Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) PUMA Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2730162)

BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

PUMA Protein (AA 1-193) (His tag) (ABIN7504951)

BBC3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE. Imm

PUMA 蛋白 by Origin

Find PUMA 蛋白 for a variety of species such as anti-Human PUMA, anti-Rat PUMA, anti-Mouse PUMA. The species listed below are among those available. Click on a link to go to the corresponding products.

PUMA 蛋白 by Source

Here you will find PUMA 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PUMA 蛋白 by 蛋白类型

Here you can find PUMA 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

PUMA 蛋白 by 应用范围

Find PUMA 蛋白 validated for a specific application such as ELISA, WB, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PUMA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121980
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2730162
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7504951
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395239
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3089700
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3128059
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2468998
Quantity 0.05 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2730161
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1623829
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PUMA 蛋白

Carpenter, Han, Paw, Lo: "HER2 phosphorylates and destabilizes pro-apoptotic PUMA, leading to antagonized apoptosis in cancer cells." in: PLoS ONE, Vol. 8, Issue 11, pp. e78836, (2013) (PubMed).

Aliases for PUMA 蛋白

BCL2 binding component 3 (BBC3) 蛋白
Bcl-2 binding component 3 (Bbc3) 蛋白
BCL2 binding component 3 (Bbc3) 蛋白
BCL2 binding component 3 (bbc3) 蛋白
BBC3 蛋白
JFY-1 蛋白
JFY1 蛋白
Puma 蛋白
PUMA 蛋白
PUMA/JFY1 蛋白
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