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PTTG1 抗体

(Pituitary Tumor-Transforming 1 (PTTG1))
The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. [provided by RefSeq, Jul 2008].
PTTG1 抗体  (AA 2-199) PTTG1 抗体  (AA 2-199) PTTG1 抗体 (AA 2-199) (ABIN7444319)

PTTG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PTTG1 抗体  (Internal Region) PTTG1 抗体  (Internal Region) PTTG1 抗体 (Internal Region) (ABIN6391382)

Verified PTTG1 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

PTTG1 抗体  (AA 1-202) PTTG1 抗体  (AA 1-202) PTTG1 抗体 (AA 1-202) (ABIN6146486)

PTTG1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

PTTG1 抗体 by Grade

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PTTG1 抗体 by 适用

Find PTTG1 抗体 for a variety of species such as anti-Human PTTG1, anti-Mouse PTTG1, anti-Rat PTTG1. The species listed below are among those available. Click on a link to go to the corresponding products.

PTTG1 抗体 by 应用范围

Find PTTG1 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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PTTG1 抗体 by 抗原表位

Find PTTG1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PTTG1 抗体 by 克隆形成能力

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PTTG1 抗体 by 克隆

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PTTG1 抗体 by 标记

Find PTTG1 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PTTG1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7444319
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF, FACS
Validations
  • (5)
Cat. No. ABIN6391382
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6146486
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN948782
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN5014129
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN391532
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (2)
Cat. No. ABIN522692
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN735803
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7168744
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN563987
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN522691
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN522694
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN563988
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN1533781
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN1533575
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PTTG1 抗体

Hong, Joo, Park, Seo, Kim, Shin, Cheong, Lee, Kim: "Extraciliary roles of the ciliopathy protein JBTS17 in mitosis and neurogenesis." in: Annals of neurology, Vol. 86, Issue 1, pp. 99-115, (2019) (PubMed).

Cui, Xu, Song, Zhao, Liu, Song: "Pituitary tumor transforming gene: a novel therapeutic target for glioma treatment." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 6, pp. 414-21, (2015) (PubMed).

Zhang, Liu, Xu, Huang, Tan, Sun, Lu: "Pituitary tumor-transforming gene 1 (PTTG1) is overexpressed in oral squamous cell carcinoma (OSCC) and promotes migration, invasion and epithelial-mesenchymal transition (EMT) in SCC15 cells." in: Tumour biology, Vol. 35, Issue 9, pp. 8801-11, (2014) (PubMed).

Aliases for PTTG1 抗体

pituitary tumor-transforming 1 (PTTG1) 抗体
pituitary tumor-transforming gene 1 (Pttg1) 抗体
pituitary tumor-transforming 1 (Pttg1) 抗体
securin, sister chromatid separation inhibitor (cut2) 抗体
AW555095 抗体
C87862 抗体
EAP1 抗体
HPTTG 抗体
Protein Cut2 抗体
PTTG 抗体
Pttg 抗体
PTTG1 抗体
Pttg3 抗体
securin 抗体
Securin 抗体
TUTR1 抗体
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