PTPRT 产品
(Receptor Protein Tyrosine Phosphatase (PTPRT))
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
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PTPRT 抗体
High quality antibodies with extensive validation data.
PTPRT ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended PTPRT 抗体
Product
Reactivity
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Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7002666
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN185288
Quantity
100 μg
Datasheet
Datasheet
Recommended PTPRT ELISA试剂盒
Latest Publications for our PTPRT Products
: "Tumor-derived extracellular mutations of PTPRT /PTPrho are defective in cell adhesion." in: Molecular cancer research : MCR, Vol. 6, Issue 7, pp. 1106-13, (2008) (PubMed).: "Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 10, pp. 4060-4, (2007) (PubMed).
: "Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT)." in: Brain research, Vol. 1116, Issue 1, pp. 50-7, (2006) (PubMed).
: "Mutational analysis of the tyrosine phosphatome in colorectal cancers." in: Science (New York, N.Y.), Vol. 304, Issue 5674, pp. 1164-6, (2004) (PubMed).
Synonyms and alternative names related to PTPRT
protein tyrosine phosphatase, receptor type T (PTPRT), protein tyrosine phosphatase, receptor type, T (Ptprt), mKIAA0283, RPTP-rfo, RPTPrhoProtein level used designations for PTPRT
- R-PTP-T
- RPTP-rho
- receptor protein tyrosine phosphatase
- receptor-type tyrosine-protein phosphatase T
- receptor-type tyrosine-protein phosphatase rho
- RPTPmam4
- mRPTPrho
- receptor protein tyrosine phosphatase-rho
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