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PTPRO 产品

(Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))
This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011].

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Featured PTPRO Categories

PTPRO 抗体

High quality antibodies with extensive validation data.

PTPRO ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PTPRO 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTPRO 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7443191
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7167513
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN519536
Quantity 100 μg
Datasheet Datasheet

Recommended PTPRO ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116825
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116826
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN512310
Quantity 96 tests
Datasheet Datasheet

Recommended PTPRO 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316881
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316883
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421806
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PTPRO Products

Zhang, Hou, Wang, Jiang, Yin, Ji, Deng, Huang, Wang, Sun: "PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis." in: Oncotarget, Vol. 6, Issue 11, pp. 9420-33, (2015) (PubMed).

Yu, Lin, Arshadi, Kalatskaya, Xue, Haider, Nguyen, Boutros, Elson, Muthuswamy, Tonks, Muthuswamy: "Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation." in: Molecular and cellular biology, Vol. 32, Issue 19, pp. 3913-24, (2012) (PubMed).

Synonyms and alternative names related to PTPRO

protein tyrosine phosphatase, receptor type O (PTPRO), protein tyrosine phosphatase, receptor type, O (Ptpro), protein tyrosine phosphatase, receptor type O (Ptpro), D28, GLEPP1, NPHS6, PTP-OC, PTP-U2, PTPBK, Ptpn15, PTPoc, PTPphi, PTPROt, PTPROT, PTPU2, R-PTP-O, RPTP-BK

Protein level used designations for PTPRO

  • glomerular epithelial protein 1
  • osteoclastic phosphotyrosyl phosphatase
  • Glomerular epithelial protein 1
  • receptor-type protein tyrosine phosphatase D30
  • receptor-type tyrosine-protein phosphatase O
  • PTPase U2
  • protein tyrosine phosphatase U2
  • protein tyrosine phosphatase, non-receptor type 15
  • receptor protein tyrosine phosphatase RO
  • PTP phi
  • osteoclastic transmembrane protein-tyrosine phosphatase
  • phosphotyrosine phosphatase U2
  • protein tyrosine phosphatase PTP-U2
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