PTPRM 产品
(Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
Categories
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008].
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Featured PTPRM Categories
Recommended PTPRM 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
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- (3)
Cat. No.
ABIN5684049
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
- (2)
Cat. No.
ABIN7440158
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN7238327
Quantity
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Datasheet
Datasheet
Recommended PTPRM 蛋白
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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
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Source
Wheat germ
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- (1)
Cat. No.
ABIN1316875
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406473
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
Cat. No.
ABIN3149771
Quantity
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Datasheet
Datasheet
Latest Publications for our PTPRM Products
: "Molecular analysis of receptor protein tyrosine phosphatase mu-mediated cell adhesion." in: The EMBO journal, Vol. 25, Issue 4, pp. 701-12, (2006) (PubMed).Synonyms and alternative names related to PTPRM
protein tyrosine phosphatase, receptor type, M, a (ptprma), protein tyrosine phosphatase, receptor type M (PTPRM), protein tyrosine phosphatase, receptor type, M, b (ptprmb), protein tyrosine phosphatase, receptor type M (ptprm), receptor-type tyrosine-protein phosphatase mu (LOC100550127), receptor-type tyrosine-protein phosphatase mu (LOC100564083), protein tyrosine phosphatase, receptor type, M (Ptprm), cb984, hR-PTPu, mKIAA4044, p-ptp-mu, ptprl1, PTPRL1, ptprm, PTPRM, R-PTP-MU, r-ptpu, rptpm, RPTPM, RPTPmu, rptpu, RPTPU, zgc:110218Protein level used designations for PTPRM
- receptor-type tyrosine-protein phosphatase mu
- protein tyrosine phosphatase, receptor type, M
- receptor-type tyrosine-protein phosphatase mu-like
- protein tyrosine phosphatase mu
- protein tyrosine phosphatase, receptor type, mu polypeptide
- protein-tyrosine phosphatase mu
- R-PTP-mu
- protein tyrosine phosphatase, receptor-type, M
- protein tyrosine phosphatase receptor-type M
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