PTPRM 产品
(Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008].
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Latest Publications for our PTPRM Products
: "Molecular analysis of receptor protein tyrosine phosphatase mu-mediated cell adhesion." in: The EMBO journal, Vol. 25, Issue 4, pp. 701-12, (2006) (PubMed).Synonyms and alternative names related to PTPRM
protein tyrosine phosphatase, receptor type, M, a (ptprma), protein tyrosine phosphatase, receptor type M (PTPRM), protein tyrosine phosphatase, receptor type, M, b (ptprmb), protein tyrosine phosphatase, receptor type M (ptprm), receptor-type tyrosine-protein phosphatase mu (LOC100550127), receptor-type tyrosine-protein phosphatase mu (LOC100564083), protein tyrosine phosphatase, receptor type, M (Ptprm), cb984, hR-PTPu, mKIAA4044, p-ptp-mu, ptprl1, PTPRL1, ptprm, PTPRM, R-PTP-MU, r-ptpu, rptpm, RPTPM, RPTPmu, rptpu, RPTPU, zgc:110218Protein level used designations for PTPRM
- receptor-type tyrosine-protein phosphatase mu
- protein tyrosine phosphatase, receptor type, M
- receptor-type tyrosine-protein phosphatase mu-like
- protein tyrosine phosphatase mu
- protein tyrosine phosphatase, receptor type, mu polypeptide
- protein-tyrosine phosphatase mu
- R-PTP-mu
- protein tyrosine phosphatase, receptor-type, M
- protein tyrosine phosphatase receptor-type M
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