PTPRF 产品
(Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
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Featured PTPRF Categories
PTPRF 抗体
High quality antibodies with extensive validation data.
PTPRF ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PTPRF 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTPRF 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ICC, IHC, IP
Validations
- (4)
Cat. No.
ABIN7444742
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, FACS, IHC, Neut
Validations
- (4)
Cat. No.
ABIN7193270
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7167505
Quantity
100 μg
Datasheet
Datasheet
Recommended PTPRF ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969749
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958952
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1154935
Quantity
96 tests
Datasheet
Datasheet
Recommended PTPRF 蛋白
Latest Publications for our PTPRF Products
: "A new 12-gene diagnostic biomarker signature of melanoma revealed by integrated microarray analysis." in: PeerJ, Vol. 1, pp. e49, (2013) (PubMed).: "Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses." in: Journal of cell science, Vol. 126, Issue Pt 21, pp. 4926-38, (2013) (PubMed).
: "Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 47263-9, (2002) (PubMed).
: "Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule." in: Molecular cancer research : MCR, Vol. 1, Issue 2, pp. 155-63, (2002) (PubMed).
: "Galpha(i2) enhances insulin signaling via suppression of protein-tyrosine phosphatase 1B." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 39705-12, (2001) (PubMed).
: "Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 9, pp. 5187-92, (2001) (PubMed).
: "Use of an antisense strategy to dissect the signaling role of protein-tyrosine phosphatase alpha." in: The Journal of biological chemistry, Vol. 274, Issue 37, pp. 26105-12, (1999) (PubMed).
: "Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression." in: The Journal of biological chemistry, Vol. 268, Issue 35, pp. 26503-11, (1994) (PubMed).
: "The SJL/J T cell response to both spontaneous and transplantable syngeneic reticulum cell sarcoma is mediated predominantly by the V beta 17a+ T cell clonotype." in: The Journal of experimental medicine, Vol. 168, Issue 5, pp. 1553-62, (1988) (PubMed).
Synonyms and alternative names related to PTPRF
protein tyrosine phosphatase, receptor type F (PTPRF), protein tyrosine phosphatase, receptor type, F (Ptprf), protein tyrosine phosphatase, receptor type, f, a (ptprfa), AA591035, LAR, LARFN5C, LARS, RPTP-LAR, zf-LARProtein level used designations for PTPRF
- LCA-homolog
- leukocyte antigen-related (LAR) PTP receptor
- leukocyte antigen-related tyrosine phosphatase
- leukocyte common antigen related
- protein tyrosine phosphatase, receptor type, F polypeptide
- receptor-linked protein-tyrosine phosphatase LAR
- receptor-type tyrosine-protein phosphatase F
- LAR
- protein tyrosine phosphatase receptor-type F
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