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PTPRE 产品

(Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains\; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Jul 2008].

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Featured PTPRE Categories

PTPRE 抗体

High quality antibodies with extensive validation data.

PTPRE 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTPRE 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7167503
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Dog, Hamster, Horse, Human, Monkey
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1049273
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6146460
Quantity 100 μL
Datasheet Datasheet

Recommended PTPRE ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6233005
Quantity 96 tests
Datasheet Datasheet

Recommended PTPRE 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316865
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419445
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1330446
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PTPRE Products

Bhattarai, McLinden, Xiang, Mathahs, Schmidt, Kaufman, Stapleton: "Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo." in: PLoS pathogens, Vol. 13, Issue 2, pp. e1006232, (2017) (PubMed).

Zheng, Resnick, Shalloway: "Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi." in: International journal of cancer, Vol. 122, Issue 9, pp. 1999-2007, (2008) (PubMed).

Toledano-Katchalski, Tiran, Sines, Shani, Granot-Attas, den Hertog, Elson: "Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon." in: Molecular and cellular biology, Vol. 23, Issue 15, pp. 5460-71, (2003) (PubMed).

Wabakken, Hauge, Funderud, Aasheim: "Characterization, expression and functional aspects of a novel protein tyrosine phosphatase epsilon isoform." in: Scandinavian journal of immunology, Vol. 56, Issue 3, pp. 276-85, (2002) (PubMed).

Blanchetot, Tertoolen, Overvoorde, den Hertog: "Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 47263-9, (2002) (PubMed).

Synonyms and alternative names related to PTPRE

protein tyrosine phosphatase, receptor type E L homeolog (ptpre.L), protein tyrosine phosphatase, receptor type E (PTPRE), protein tyrosine phosphatase, receptor type, E (Ptpre), HPTPE, PTPE, PTPe, PTPepsilon, ptpra, R-PTP-EPSILON, RPTPepsilon

Protein level used designations for PTPRE

  • protein tyrosine phosphatase, receptor type, A
  • receptor-type tyrosine-protein phosphatase epsilon
  • protein tyrosine phosphatase, receptor type, epsilon polypeptide
  • R-PTP-epsilon
  • protein-tyrosine phosphatase epsilon
  • protein tyrosine phosphatase epsilon
  • protein tyrosine phosphatase epsilon-like 1
  • protein tyrosine phosphatase epsilon-like 2
  • protein tyrosine phosphatase, receptor type, epsilon
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