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PTPRA 产品

(Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].

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Featured PTPRA Categories

PTPRA 抗体

High quality antibodies with extensive validation data.

PTPRA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PTPRA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTPRA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN1682399
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC
Validations
  • (3)
Cat. No. ABIN7260017
Quantity 200 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1049270
Quantity 50 μg
Datasheet Datasheet

Recommended PTPRA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1154921
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1154922
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951512
Quantity 96 tests
Datasheet Datasheet

Recommended PTPRA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419442
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419745
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN7509248
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our PTPRA Products

Wu, Kao, Li, Chi, Lin: "Protein tyrosine-phosphatase expression profiling in gastric cancer tissues." in: Cancer letters, Vol. 242, Issue 1, pp. 95-103, (2006) (PubMed).

Yahiro, Wada, Nakayama, Kimura, Ogushi, Niidome, Aoyagi, Yoshino, Yonezawa, Moss, Hirayama: "Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor." in: The Journal of biological chemistry, Vol. 278, Issue 21, pp. 19183-9, (2003) (PubMed).

Zhang, Kondrikov, Yuan, Lin, Hansen, Lin: "Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells." in: Oncogene, Vol. 22, Issue 43, pp. 6704-16, (2003) (PubMed).

Kapp, Metzinger, Kellerer, Häring, Lammers: "The protein tyrosine phosphatase alpha modifies insulin secretion in INS-1E cells." in: Biochemical and biophysical research communications, Vol. 311, Issue 2, pp. 361-4, (2003) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Zheng, Pallen: "Expression of receptor-like protein tyrosine phosphatase alpha in rat embryo fibroblasts activates mitogen-activated protein kinase and c-Jun." in: The Journal of biological chemistry, Vol. 269, Issue 37, pp. 23302-9, (1994) (PubMed).

Zheng, Wang, Pallen: "Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase." in: Nature, Vol. 359, Issue 6393, pp. 336-9, (1992) (PubMed).

Sap, DEustachio, Givol, Schlessinger: "Cloning and expression of a widely expressed receptor tyrosine phosphatase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 16, pp. 6112-6, (1990) (PubMed).

Synonyms and alternative names related to PTPRA

protein tyrosine phosphatase, receptor type A (PTPRA), protein tyrosine phosphatase, receptor type A (ptpra), protein tyrosine phosphatase, receptor type, A (PTPRA), protein tyrosine phosphatase, receptor type, A (Ptpra), protein tyrosine phosphatase, receptor type, A (ptpra), protein tyrosine phosphatase, receptor type A S homeolog (ptpra.S), heptp, HEPTP, hlpr, HLPR, hptpa, HPTPA, hptpalpha, HPTPalpha, lrp, LRP, ptpa, PTPA, Ptpa, ptpa-a, Ptpalpha, PTPRA, ptprl2, PTPRL2, r-ptp-alpha, R-PTP-alpha, rptpa, RPTPA, Rptpalpha, RPTP[a], Rptra, Rptralpha, zf-RPTP[a]

Protein level used designations for PTPRA

  • protein tyrosine phosphatase, receptor type, A
  • receptor-type tyrosine-protein phosphatase alpha-like
  • Leukocyte common antigen-related peptide (protein tyrosine phosphate)
  • PTPLCA-related phosphatase
  • PTPase-alpha
  • protein tyrosine phosphatase, receptor type, alpha polypeptide
  • protein-tyrosine phosphatase alpha
  • receptor-type tyrosine-protein phosphatase alpha
  • tyrosine phosphatase alpha
  • LCA-related phosphatase
  • PTPTY-28
  • R-PTP-alpha
  • protein tyrosine phosphatase alpha
  • protein tyrosine phosphatase receptor type alpha
  • protein-tyrosine-phosphatase alpha
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