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PTPN5 产品

(Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5))

Categories

May regulates the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors (By similarity).

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Featured PTPN5 Categories

PTPN5 抗体

High quality antibodies with extensive validation data.

PTPN5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTPN5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7444961
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7174112
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7269705
Quantity 100 μL
Datasheet Datasheet

Recommended PTPN5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232132
Quantity 96 tests
Datasheet Datasheet

Recommended PTPN5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316847
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316849
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419409
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PTPN5 Products

Pose-Utrilla, García-Guerra, Del Puerto, Martín, Jurado-Arjona, De León-Reyes, Gamir-Morralla, Sebastián-Serrano, García-Gallo, Kremer, Fielitz, Ireson, Pérez-Álvarez, Ferrer, Hernández, Ávila, Lasa et al.: "Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1. ..." in: Nature communications, Vol. 8, Issue 1, pp. 2275, (2018) (PubMed).

Carvajal, Mira, Rovegno, Minniti, Cerpa: "Age-related NMDA signaling alterations in SOD2 deficient mice." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1864, Issue 6 Pt A, pp. 2010-2020, (2018) (PubMed).

Poddar, Rajagopal, Shuttleworth, Paul: "Zn2+-dependent Activation of the Trk Signaling Pathway Induces Phosphorylation of the Brain-enriched Tyrosine Phosphatase STEP: MOLECULAR BASIS FOR ZN2+-INDUCED ERK MAPK ACTIVATION." in: The Journal of biological chemistry, Vol. 291, Issue 2, pp. 813-25, (2016) (PubMed).

Rajagopal, Deb, Poddar, Paul: "Aging is associated with dimerization and inactivation of the brain-enriched tyrosine phosphatase STEP." in: Neurobiology of aging, Vol. 41, pp. 25-38, (2016) (PubMed).

Won, Incontro, Nicoll, Roche: "PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 32, pp. E4736-44, (2016) (PubMed).

Kim, Jang, Choi: "A single fraction from Uncaria sinensis exerts neuroprotective effects against glutamate-induced neurotoxicity in primary cultured cortical neurons." in: Anatomy & cell biology, Vol. 48, Issue 2, pp. 95-103, (2015) (PubMed).

Sun, Zelek-Molik, McGinty: "Short and long access to cocaine self-administration activates tyrosine phosphatase STEP and attenuates GluN expression but differentially regulates GluA expression in the prefrontal cortex." in: Psychopharmacology, Vol. 229, Issue 4, pp. 603-13, (2013) (PubMed).

Kim, Kim, Jang, Choi, Baek, Hong, Choi, Shin, Choi: "Neuroprotective effects of Polygonum multiflorum extract against glutamate-induced oxidative toxicity in HT22 hippocampal cells." in: Journal of ethnopharmacology, Vol. 150, Issue 1, pp. 108-15, (2013) (PubMed).

Deb, Manhas, Poddar, Rajagopal, Allan, Lombroso, Rosenberg, Candelario-Jalil, Paul: "Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 45, pp. 17814-26, (2013) (PubMed).

Wang, Briz, Chishti, Bi, Baudry: "Distinct roles for μ-calpain and m-calpain in synaptic NMDAR-mediated neuroprotection and extrasynaptic NMDAR-mediated neurodegeneration." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 48, pp. 18880-92, (2013) (PubMed).

Synonyms and alternative names related to PTPN5

protein tyrosine phosphatase, non-receptor type 5 (ptpn5), protein tyrosine phosphatase, non-receptor type 5 (PTPN5), protein tyrosine phosphatase, non-receptor type 5 (Ptpn5), PTPSTEP, STEP, Step

Protein level used designations for PTPN5

  • protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
  • tyrosine-protein phosphatase non-receptor type 5
  • neural-specific protein-tyrosine phosphatase
  • protein-tyrosine phosphatase striatum-enriched
  • protein-tyrosine-phosphatase non-receptor 5
  • striatum-enriched protein-tyrosine phosphatase
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