PTPN22 产品
(Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))
Categories
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009].
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Featured PTPN22 Categories
Recommended PTPN22 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF, FACS
Validations
- (5)
Cat. No.
ABIN6391380
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN1513449
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN565235
Quantity
100 μg
Datasheet
Datasheet
Recommended PTPN22 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971027
Quantity
96 tests
Datasheet
Datasheet
Recommended PTPN22 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1316837
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316839
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422139
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PTPN22 Products
: "Measuring the specific activity of the protein tyrosine phosphatase Lyp." in: Journal of immunological methods, Vol. 388, Issue 1-2, pp. 33-9, (2013) (PubMed).: "High basal activity of the PTPN22 gain-of-function variant blunts leukocyte responsiveness negatively affecting IL-10 production in ANCA vasculitis." in: PLoS ONE, Vol. 7, Issue 8, pp. e42783, (2012) (PubMed).
Synonyms and alternative names related to PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (Ptpn22), protein tyrosine phosphatase, non-receptor type 22 (PTPN22), protein tyrosine phosphatase, non-receptor type 22 (Ptpn22), 70zpep, LYP, LYP1, LYP2, PEP, Ptpn8, PTPN8Protein level used designations for PTPN22
- PEST domain-enriched tyrosine phosphatase
- hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
- protein tyrosine phosphatase, non-receptor type 8
- tyrosine-protein phosphatase non-receptor type 22
- PEST-domain phosphatase
- lymphoid phosphatase
- lymphoid-specific protein tyrosine phosphatase
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