PTPN21 产品
(Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008].
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Featured PTPN21 Categories
Recommended PTPN21 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7444973
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN392838
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (2)
Cat. No.
ABIN5014222
Quantity
100 μL
Datasheet
Datasheet
Recommended PTPN21 蛋白
Product
Reactivity
Source
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419742
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419433
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094803
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PTPN21 Products
: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." in: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).: "Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41124-32, (2001) (PubMed).
: "Expression of protein tyrosine phosphatase PTP-RL10 and its isoform in the mouse testis." in: International journal of urology : official journal of the Japanese Urological Association, Vol. 6, Issue 11, pp. 572-7, (2000) (PubMed).
Synonyms and alternative names related to PTPN21
protein tyrosine phosphatase, non-receptor type 21 (PTPN21), protein tyrosine phosphatase, non-receptor type 21 (Ptpn21), Ptp2E, PTPD1, PTPRL10Protein level used designations for PTPN21
- dJ1175B15.2 (protein tyrosine phosphatase, non-receptor type 21)
- protein tyrosine phosphatase D1
- protein-tyrosine phosphatase D1
- tyrosine-protein phosphatase non-receptor type 21
- protein-tyrosine phosphatase PTP-RL10
- protein tyrosine phosphatase 2E
- protein-tyrosine phosphatase 2E
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