PTPN2 抗体
(Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011].
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PTPN2 抗体 by 应用范围
Find PTPN2 抗体 validated for a specific application such as WB, IHC, ELISA, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.
PTPN2 抗体 by 抗体来源
Find PTPN2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
PTPN2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PTPN2 抗体. Click on a link to go to the corresponding products.
PTPN2 抗体 by 克隆
Find PTPN2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
PTPN2 抗体 by 标记
Find PTPN2 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular PTPN2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (8)
Cat. No.
ABIN3022585
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7444958
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (3)
Cat. No.
ABIN519504
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7259775
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7192064
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6738161
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN6264516
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN3043447
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN657234
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7308244
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN519503
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Chicken, Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN205078
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN630412
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
Application
WB
Validations
- (2)
Cat. No.
ABIN2782194
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2782195
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our PTPN2 抗体
: "Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2), an Important Regulator of IL-6 Production in Rheumatoid Arthritis Synovial Fibroblasts." in: Arthritis & rheumatology (Hoboken, N.J.), (2015) (PubMed).: "T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease." in: Immunological reviews, Vol. 228, Issue 1, pp. 325-41, (2009) (PubMed).
: "TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}." in: Blood, Vol. 109, Issue 10, pp. 4220-8, (2007) (PubMed).
: "Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP." in: Molecular and cellular biology, Vol. 23, Issue 6, pp. 2096-108, (2003) (PubMed).
: "Gr-1+ myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 2, pp. 726-32, (2003) (PubMed).
: "Identification of a nuclear Stat1 protein tyrosine phosphatase." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5662-8, (2002) (PubMed).
Aliases for PTPN2 抗体
protein tyrosine phosphatase, non-receptor type 2 (PTPN2) 抗体protein tyrosine phosphatase, non-receptor type 2 (Ptpn2) 抗体
protein tyrosine phosphatase, non-receptor type 2 S homeolog (ptpn2.S) 抗体
protein tyrosine phosphatase, non-receptor type 2, b (ptpn2b) 抗体
protein tyrosine phosphatase, non-receptor type 2, a (ptpn2a) 抗体
protein tyrosine phosphatase, non-receptor type 2 L homeolog (ptpn2.L) 抗体
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