PTPN13 抗体
(Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008].
recommended
recommended
PTPN13 适用: 人 ELISA, WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
PTPN13 抗体 by 适用
Find PTPN13 抗体 for a variety of species such as anti-Human PTPN13, anti-Mouse PTPN13, anti-Rat PTPN13. The species listed below are among those available. Click on a link to go to the corresponding products.
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Validations
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Application
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Cat. No.
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Datasheet
Datasheet
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Cat. No.
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Quantity
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Datasheet
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Application
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Datasheet
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Application
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Validations
Cat. No.
ABIN896762
Quantity
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Datasheet
Datasheet
Reactivity
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Application
FACS, IF (cc), IF (p)
Validations
Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
Cat. No.
ABIN2813125
Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Quantity
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Latest Publications for our PTPN13 抗体
: "Apoptotic signalling targets the post-endocytic sorting machinery of the death receptor Fas/CD95." in: Nature communications, Vol. 10, Issue 1, pp. 3105, (2019) (PubMed).: "Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway." in: International journal of molecular sciences, Vol. 18, Issue 7, (2017) (PubMed).
: "Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability." in: Nature communications, Vol. 7, pp. 11853, (2016) (PubMed).
: "Proteins interacting with cloning scars: a source of false positive protein-protein interactions." in: Scientific reports, Vol. 5, pp. 8530, (2015) (PubMed).
: "FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface." in: Molecular and cellular biology, Vol. 23, Issue 10, pp. 3623-35, (2003) (PubMed).
: "Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): splicing-induced modulation of ligand specificity." in: Journal of molecular biology, Vol. 334, Issue 1, pp. 143-55, (2003) (PubMed).
: "Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 47861-9, (2002) (PubMed).
: "Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer." in: The American journal of pathology, Vol. 158, Issue 4, pp. 1335-44, (2001) (PubMed).
Aliases for PTPN13 抗体
protein tyrosine phosphatase, non-receptor type 13 (PTPN13) 抗体tyrosine-protein phosphatase non-receptor type 13 (LOC100540743) 抗体
protein tyrosine phosphatase, non-receptor type 13 (ptpn13) 抗体
protein tyrosine phosphatase, non-receptor type 13 (Ptpn13) 抗体
AI324989 抗体
FAP-1 抗体
hPTP1E 抗体
PNP1 抗体
ptp 抗体
PTP-BAS 抗体
PTP-BL 抗体
Ptp-bl 抗体
PTP1E 抗体
PTPL1 抗体
PTPLE 抗体
PTPN13 抗体
Ptpri 抗体
RIP 抗体
wu:fb50g04 抗体
zgc:162319 抗体
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