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PTPN1 抗体

(Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. [provided by RefSeq, Jul 2008].
PTPN1 抗体 PTPN1 抗体 PTPN1 抗体 (ABIN1500496)

PTPN1 适用: 人, 猴, 犬 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D10 unconjugated

PTPN1 抗体  (AA 40-246) PTPN1 抗体  (AA 40-246) PTPN1 抗体 (AA 40-246) (ABIN5542667)

PTPN1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4F8F11 unconjugated

PTPN1 抗体  (AA 1-100) PTPN1 抗体  (AA 1-100) PTPN1 抗体 (AA 1-100) (ABIN725975)

PTPN1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

PTPN1 抗体 by 适用

Find PTPN1 抗体 for a variety of species such as anti-Human PTPN1, anti-Mouse PTPN1, anti-Rat PTPN1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find PTPN1 抗体 validated for a specific application such as WB, ELISA, FACS, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PTPN1 抗体 by 抗体来源

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PTPN1 抗体 by 抗原表位

Find PTPN1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PTPN1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PTPN1 抗体. Click on a link to go to the corresponding products.

PTPN1 抗体 by 克隆

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PTPN1 抗体 by 标记

Find PTPN1 抗体 with a specific conjugate such as Biotin, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PTPN1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Monkey
Application WB, IHC, FACS, IF, IHC (p)
Validations
  • (7)
Cat. No. ABIN1500496
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN5542667
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (4)
Cat. No. ABIN725975
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6256357
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7127784
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6264512
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN5542666
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (6)
  • (1)
Cat. No. ABIN1882122
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN1881705
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN519500
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN1327661
Quantity 50 μL
Datasheet Datasheet
Reactivity Chicken, Dog, Human, Monkey, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7301178
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7182527
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7138636
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6738160
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PTPN1 抗体

Jun, Lee, Kim, Jung, Choi, Kim, Chin, Yang: "Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models." in: Oncology reports, Vol. 34, Issue 4, pp. 2047-53, (2016) (PubMed).

Liu, Gao, Li, Geng, Xu, Yang, Guo, Jiao, Fang, Chang: "Sirt1 mediates the effect of the heme oxygenase inducer, cobalt protoporphyrin, on ameliorating liver metabolic damage caused by a high-fat diet." in: Journal of hepatology, Vol. 63, Issue 3, pp. 713-21, (2016) (PubMed).

Brobeil, Viard, Petri, Steger, Tag, Wimmer: "Memory and PTPIP51--a new protein in hippocampus and cerebellum." in: Molecular and cellular neurosciences, Vol. 64, pp. 61-73, (2015) (PubMed).

Brobeil, Graf, Eiber, Wimmer: "Interaction of PTPIP51 with Tubulin, CGI-99 and Nuf2 During Cell Cycle Progression." in: Biomolecules, Vol. 2, Issue 1, pp. 122-42, (2014) (PubMed).

Brobeil, Koch, Eiber, Tag, Wimmer: "The known interactome of PTPIP51 in HaCaT cells - inhibition of kinases and receptors." in: The international journal of biochemistry & cell biology, (2014) (PubMed).

Gan, Zhang, Buckels, Paterson, Jiang, Clemens, Zhang, Du, Chang, Frank: "IGF-1R modulation of acute GH-induced STAT5 signaling: role of protein tyrosine phosphatase activity." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 11, pp. 1969-79, (2013) (PubMed).

Brobeil, Bobrich, Tag, Wimmer: "PTPIP51 in protein interactions: regulation and in situ interacting partners." in: Cell biochemistry and biophysics, Vol. 63, Issue 3, pp. 211-22, (2012) (PubMed).

Tsou, Talia, Pinney, Kendzicky, Piera-Velazquez, Jimenez, Seibold, Phillips, Koch: "Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts." in: Arthritis and rheumatism, Vol. 64, Issue 6, pp. 1978-89, (2012) (PubMed).

Brobeil, Bobrich, Graf, Kruchten, Blau, Rummel, Oeschger, Steger, Wimmer: "PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia." in: Leukemia research, Vol. 35, Issue 10, pp. 1367-75, (2011) (PubMed).

Stuible, Tremblay: "In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis." in: Trends in cell biology, Vol. 20, Issue 11, pp. 672-9, (2010) (PubMed).

Aliases for PTPN1 抗体

protein tyrosine phosphatase, non-receptor type 1 (PTPN1) 抗体
protein tyrosine phosphatase, non-receptor type 1 (Ptpn1) 抗体
protein tyrosine phosphatase, non-receptor type 1 (ptpn1) 抗体
protein tyrosine phosphatase, non-receptor type 1 L homeolog (ptpn1.L) 抗体
CPTP1 抗体
Ptp 抗体
PTP-1B 抗体
PTP-HA2 抗体
PTP1B 抗体
ptp1b 抗体
PTPN1 抗体
wu:fk54h03 抗体
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