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PTP4A1 产品

(Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))

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The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq, Jul 2008].

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Featured PTP4A1 Categories

PTP4A1 抗体

High quality antibodies with extensive validation data.

PTP4A1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTP4A1 抗体

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Reactivity Human, Mouse
Application WB, ELISA, IF
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Cat. No. ABIN185274
Quantity 100 μg
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Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
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Cat. No. ABIN6264513
Quantity 100 μL
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Reactivity Human, Mouse, Rat
Application ELISA, IHC
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Cat. No. ABIN7245674
Quantity 200 μL
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Recommended PTP4A1 蛋白

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Source Escherichia coli (E. coli)
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Cat. No. ABIN7275477
Quantity 100 μg
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Reactivity Human
Source Escherichia coli (E. coli)
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Cat. No. ABIN7124677
Quantity 50 μg
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1316799
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Latest Publications for our PTP4A1 Products

Min, Kim, Heo, Kim, Kim, Kim, Han, Kim, Yoo: "New p53 target, phosphatase of regenerating liver 1 (PRL-1) downregulates p53." in: Oncogene, Vol. 28, Issue 4, pp. 545-54, (2009) (PubMed).

Achiwa, Lazo: "PRL-1 tyrosine phosphatase regulates c-Src levels, adherence, and invasion in human lung cancer cells." in: Cancer research, Vol. 67, Issue 2, pp. 643-50, (2007) (PubMed).

Jeong, Kim, Kim, Son, Park, Lim, Yoon, Ryu: "Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms." in: Journal of molecular biology, Vol. 345, Issue 2, pp. 401-13, (2004) (PubMed).

Werner, Lee, DeCamp, Crowell, Randall, Crowell: "Enhanced cell cycle progression and down regulation of p21(Cip1/Waf1) by PRL tyrosine phosphatases." in: Cancer letters, Vol. 202, Issue 2, pp. 201-11, (2003) (PubMed).

Wang, Kirby, Herbst: "The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis." in: The Journal of biological chemistry, Vol. 277, Issue 48, pp. 46659-68, (2002) (PubMed).

Peng, Genin, Spinner, Diamond, Taub: "The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 17286-95, (1998) (PubMed).

Synonyms and alternative names related to PTP4A1

protein tyrosine phosphatase type IVA, member 1 (PTP4A1), protein tyrosine phosphatase type IVA, member 1 L homeolog (ptp4a1.L), protein tyrosine phosphatase type IVA, member 1 (ptp4a1), protein tyrosine phosphatase type IVA, member 1 (Ptp4a1), protein tyrosine phosphatase 4a1 (Ptp4a1), AA415290, AU019864, C130021B01, DKFZp459E022, fb54d08, fc01c04, hh72, HH72, MGC79517, MGC83351, prl-1, PRL-1, Prl-1, prl1, PRL1, ptp(caax1), PTP(CAAX1), ptp4a1, Ptp4a1, PTP4A1, ptpcaax1, PTPCAAX1, wu:fb54d08, wu:fc01c04, zgc:101726

Protein level used designations for PTP4A1

  • protein tyrosine phosphatase type IVA 1
  • protein tyrosine phosphatase type IVA, member 1
  • PRL-1
  • Protein tyrosine phosphatase type IVA 1
  • protein-tyrosine phosphatase 4a1
  • protein-tyrosine phosphatase of regenerating liver 1
  • protein tyrosine phosphatase type IVA protein 1
  • protein tyrosine phosphatase 4a1
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