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PTK7 产品

(PTK7 Protein tyrosine Kinase 7 (PTK7))

Categories

This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].

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Featured PTK7 Categories

PTK7 抗体

High quality antibodies with extensive validation data.

PTK7 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTK7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN519485
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (4)
Cat. No. ABIN1497127
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6146429
Quantity 100 μL
Datasheet Datasheet

Recommended PTK7 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974488
Quantity 96 tests
Datasheet Datasheet

Recommended PTK7 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274039
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274040
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316785
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PTK7 Products

Wang, Li, Yin, Wang, Wang, Wei, Guo, Ma, Shi, Zhou, Wang: "PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis." in: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7881-9, (2014) (PubMed).

Golubkov, Strongin: "Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells." in: Cell communication and signaling : CCS, Vol. 12, pp. 15, (2014) (PubMed).

Golubkov, Prigozhina, Zhang, Stoletov, Lewis, Schwartz, Hoffman, Strongin: "Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis." in: The Journal of biological chemistry, Vol. 289, Issue 35, pp. 24238-49, (2014) (PubMed).

Chen, Khatri, Mazur, Polin, Zheng, Vaka, Hoang, Shrager, Xu, Vicent, Butte, Sweet-Cordero: "A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma." in: Cancer research, Vol. 74, Issue 10, pp. 2892-902, (2014) (PubMed).

Golubkov, Chekanov, Cieplak, Aleshin, Chernov, Zhu, Radichev, Zhang, Dong, Strongin: "The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis." in: The Journal of biological chemistry, Vol. 285, Issue 46, pp. 35740-9, (2010) (PubMed).

Haines, Giffon, Lu, Lu, Tessier-Lavigne, Ross, Lewis: "Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 275-85, (2009) (PubMed).

Shin, Maeng, Jung, Min, Kwon, Lee: "Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis." in: Biochemical and biophysical research communications, Vol. 371, Issue 4, pp. 793-8, (2008) (PubMed).

Müller-Tidow, Schwäble, Steffen, Tidow, Brandt, Becker, Schulze-Bahr, Halfter, Vogt, Metzger, Schneider, Büchner, Brandts, Berdel, Serve: "High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 4, pp. 1241-9, (2004) (PubMed).

Lu, Borchers, Jolicoeur, Rayburn, Baker, Tessier-Lavigne: "PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates." in: Nature, Vol. 430, Issue 6995, pp. 93-8, (2004) (PubMed).

Zhang, Li, Martin, Aebersold: "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry." in: Nature biotechnology, Vol. 21, Issue 6, pp. 660-6, (2003) (PubMed).

Synonyms and alternative names related to PTK7

protein tyrosine kinase 7 (inactive) (PTK7), protein tyrosine kinase 7 (Ptk7), PTK7 protein tyrosine kinase 7 (Ptk7), 8430404F20Rik, CCK-4, CCK4, chz, KLG, mPTK7/CCK4, PTK7, Srf

Protein level used designations for PTK7

  • PTK7 protein tyrosine kinase 7
  • inactive tyrosine-protein kinase 7
  • tyrosine-protein kinase-like 7-like
  • colon carcinoma kinase 4
  • pseudo tyrosine kinase receptor 7
  • tyrosine-protein kinase-like 7
  • serum response factor
  • protein chuzhoi
  • protein-tyrosine kinase 7
  • receptor tyrosine kinase-like protein
  • kinase-like protein
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