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PTGIS 产品

(Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008].

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Featured PTGIS Categories

PTGIS 抗体

High quality antibodies with extensive validation data.

PTGIS ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PTGIS 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTGIS 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN6259069
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN562513
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN519453
Quantity 100 μg
Datasheet Datasheet

Recommended PTGIS ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958871
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969667
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969666
Quantity 96 tests
Datasheet Datasheet

Recommended PTGIS 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316752
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316750
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391885
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PTGIS Products

Mao, Smoake, Park, Lu, Xue: "Grape Seed Procyanidin Extract Mediates Antineoplastic Effects against Lung Cancer via Modulations of Prostacyclin and 15-HETE Eicosanoid Pathways." in: Cancer prevention research (Philadelphia, Pa.), Vol. 9, Issue 12, pp. 925-932, (2016) (PubMed).

Gurgul-Convey, Hanzelka, Lenzen: "Mechanism of prostacyclin-induced potentiation of glucose-induced insulin secretion." in: Endocrinology, Vol. 153, Issue 6, pp. 2612-22, (2012) (PubMed).

Synonyms and alternative names related to PTGIS

prostaglandin I2 synthase (PTGIS), prostaglandin I2 (prostacyclin) synthase (Ptgis), prostaglandin I2 (prostacyclin) synthase (ptgis), prostacyclin synthase (VDBG_06319), prostaglandin I2 synthase (Ptgis), CYP8, Cyp8, CYP8A1, Cyp8a1, PGIS, Pgis, PTGI, PTGIS, ptgisl

Protein level used designations for PTGIS

  • cytochrome P450, family 8, subfamily A, polypeptide 1
  • prostacyclin synthase
  • prostaglandin I2 synthase
  • prostaglandin I2 (prostacyclin) synthase like
  • prostaglandin I2 (prostacyclin) synthase
  • cytochrome P450 8A1
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