PTGER4 产品
(Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))
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The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008].
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Recommended PTGER4 抗体
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Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Rat
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IHC (p), IHC, ICC
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- (5)
Cat. No.
ABIN1049258
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50 μg
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Human, Monkey
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IHC (p), IHC, ICC
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Cat. No.
ABIN1049257
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50 μg
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Human
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WB, ELISA, IF, ICC
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ABIN6259076
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Recommended PTGER4 蛋白
Latest Publications for our PTGER4 Products
: "Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice." in: JCI insight, Vol. 3, Issue 3, (2018) (PubMed).: "Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis." in: International journal of molecular sciences, Vol. 18, Issue 12, (2018) (PubMed).
: "GW627368X inhibits proliferation and induces apoptosis in cervical cancer by interfering with EP4/EGFR interactive signaling." in: Cell death & disease, Vol. 7, pp. e2154, (2016) (PubMed).
: "Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells." in: Endocrinology, Vol. 157, Issue 2, pp. 692-704, (2016) (PubMed).
: "The expression of prostaglandin-E2 and its receptor in the oviduct of Chinese brown frog (Rana dybowskii)." in: Prostaglandins & other lipid mediators, Vol. 124, pp. 9-15, (2016) (PubMed).
: "Molecular inhibition of prostaglandin E2 with GW627368X: Therapeutic potential and preclinical safety assessment in mouse sarcoma model." in: Cancer biology & therapy, Vol. 16, Issue 6, pp. 922-32, (2015) (PubMed).
: "Cell entry of bovine ephemeral fever virus requires activation of Src-JNK-AP1 and PI3K-Akt-NF-κB pathways as well as Cox-2-mediated PGE2 /EP receptor signalling to enhance clathrin-mediated virus ..." in: Cellular microbiology, Vol. 17, Issue 7, pp. 967-87, (2015) (PubMed).
: "Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 154, (2015) (PubMed).
: "Chemo-sensitizing effects of EP4 receptor-induced inactivation of nuclear factor-κB." in: European journal of pharmacology, Vol. 742, pp. 81-8, (2014) (PubMed).
: "Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties." in: Breast cancer research and treatment, Vol. 143, Issue 1, pp. 19-31, (2014) (PubMed).
Synonyms and alternative names related to PTGER4
prostaglandin E receptor 4 (PTGER4), prostaglandin E receptor 4 (subtype EP4) (PTGER4), prostaglandin E receptor 4 (subtype EP4) a (ptger4a), prostaglandin E receptor 4 (ptger4), prostaglandin E receptor 4 subtype EP4 (ptger4), prostaglandin E receptor 4 (subtype EP4) (Ptger4), prostaglandin E receptor 4 (Ptger4), EP4, ep4, EP4R, PGE2R-EP4, Ptger, ptger4, PTGER4, ptger4l, Ptgerep4Protein level used designations for PTGER4
- prostaglandin E receptor 4, subtype EP4
- prostaglandin E2 receptor EP4 subtype
- prostaglandin E2 receptor subtype 4
- prostaglandin E receptor 4 (subtype EP4)
- ep4
- ep4a
- prostaglandin E receptor 4
- prostaglandin E receptor 4 subtype EP4
- PGE receptor EP4 subtype
- PGE receptor, EP4 subtype
- PGE2 receptor EP4 subtype
- prostanoid EP4 receptor
- prostaglandin E receptor 4 (EP4 subtype)
- prostaglandin E receptor EP4 subtype
- prostaglandin E2 receptor type 4
- PGE receptor, subtype EP4
- prostaglandin receptor EP4 subtype
- prostaglandin E2 subtype EP4 receptor
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