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PTCRA 产品

(Pre T-Cell Antigen Receptor alpha (PTCRA))

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The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011].

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Featured PTCRA Categories

PTCRA 抗体

High quality antibodies with extensive validation data.

PTCRA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our PTCRA Products

Aifantis, Feinberg, Fehling, Di Santo, von Boehmer: "Early T cell receptor beta gene expression is regulated by the pre-T cell receptor-CD3 complex." in: The Journal of experimental medicine, Vol. 190, Issue 1, pp. 141-4, (1999) (PubMed).

Aifantis, Pivniouk, Gärtner, Feinberg, Swat, Alt, von Boehmer, Geha: "Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein." in: The Journal of experimental medicine, Vol. 190, Issue 8, pp. 1093-102, (1999) (PubMed).

Wiest, Berger, Carleton: "Control of early thymocyte development by the pre-T cell receptor complex: A receptor without a ligand?" in: Seminars in immunology, Vol. 11, Issue 4, pp. 251-62, (1999) (PubMed).

von Boehmer, Aifantis, Feinberg, Lechner, Saint-Ruf, Walter, Buer, Azogui: "Pleiotropic changes controlled by the pre-T-cell receptor." in: Current opinion in immunology, Vol. 11, Issue 2, pp. 135-42, (1999) (PubMed).

Aifantis, Azogui, Feinberg, Saint-Ruf, Buer, von Boehmer: "On the role of the pre-T cell receptor in alphabeta versus gammadelta T lineage commitment." in: Immunity, Vol. 9, Issue 5, pp. 649-55, (1998) (PubMed).

von Boehmer, Fehling: "Structure and function of the pre-T cell receptor." in: Annual review of immunology, Vol. 15, pp. 433-52, (1997) (PubMed).

Synonyms and alternative names related to PTCRA

pre T cell antigen receptor alpha (Ptcra), pre T-cell antigen receptor alpha (PTCRA), pre T-cell antigen receptor alpha (Ptcra), gp33, pT-alpha, PT-ALPHA, pT-alpha-TCR, pTa, PTA, pTalpha, pT[a]

Protein level used designations for PTCRA

  • pre T-cell antigen receptor alpha
  • pT-alpha-TCR
  • pre-T-cell receptor alpha chain
  • pT-alpha
  • pTa
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